ArticleJournal of bone and mineral metabolism2018
Association between metabolic syndrome and bone mineral density in a Taiwanese elderly population.
Article in Journal of bone and mineral metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Clustering of Lifestyle Behaviors and Their Association With Risk of Metabolic Syndrome Among Adults in Taiwan: Nationwide Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Contradictory links between lipid levels and bone health: atherogenic index of plasma and bone microarchitecture.Journal of orthopaedic surgery and research · 2025Article
- Associations of obesity defined comprehensively by body mass index and body fat percentage with osteopenia.Clinics (Sao Paulo, Brazil) · 2025Article
- Lipid metabolites are associated with the risk of osteoporotic fractures.Scientific reports · 2024Article
- Association of Decreased Bone Density and Hyperlipidemia in a Taiwanese Older Adult Population.Journal of the Endocrine Society · 2024Article
- Association between Metabolic Syndrome and Musculoskeletal Status: A Cross-Sectional Study of NHANES.International journal of endocrinology · 2024Article
- Article
- Menopause modified the association of blood pressure with osteoporosis among gender: a large-scale cross-sectional study.Frontiers in public health · 2024Article
- Peak Bone Mass Formation: Modern View of the Problem.Biomedicines · 2023Review
- Effects of metabolic syndrome on bone mineral density in postmenopausal Turkish women.African health sciences · 2023Article
- Association between Adiposity and Bone Mineral Density in Adults: Insights from a National Survey Analysis.Nutrients · 2023Article
- The Impact of Metabolic Syndrome on Bone Mass in Men: Systematic Review and Meta-Analysis.Biomedicines · 2023Review
- The correlation between high-density lipoprotein cholesterol and bone mineral density in adolescents: a cross-sectional study.Scientific reports · 2023Article
- Relationships between Bone Turnover Markers and Factors Associated with Metabolic Syndrome in Prepubertal Girls and Boys.Nutrients · 2022Article
- Bone Health in Patients with Dyslipidemias: An Underestimated Aspect.International journal of molecular sciences · 2022Review
- Obesity and Bone: A Complex Relationship.International journal of molecular sciences · 2021Review
- Novel nomogram for predicting the 3-year incidence risk of osteoporosis in a Chinese male population.Endocrine connections · 2021Article
- Associations between Metabolic Syndrome and Obesity-Related Indices and Bone Mineral Density T-Score in Hemodialysis Patients.Journal of personalized medicine · 2021Article
- Machine Learning to Predict the Progression of Bone Mass Loss Associated with Personal Characteristics and a Metabolic Syndrome Scoring Index.Healthcare (Basel, Switzerland) · 2021Article
- Metabolic syndrome is associated to an increased risk of low bone mineral density in free-living women with suspected osteoporosis.Journal of endocrinological investigation · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies have demonstrated uncertainty regarding the effect of metabolic syndrome (MetS) on bone. In the present work, we investigated the association between MetS, its components, and decreased bone mineral density (BMD) in a cross-sectional study of patients who underwent BMD measurement by dual-energy X-ray absorptiometry during a health examination. Decreased BMD was defined as either osteopenia or osteoporosis. MetS components and body mass index (BMI) were compared between individuals with normal and decreased BMD, and simple and multivariate logistic regression analyses were used to evaluate the association between the variables and decreased BMD in women and men. Among 1162 subjects in the study, the mean age was 59.9 ± 7.3 years, and 59.5% were men. The prevalence of MetS and osteoporosis was 34.2 and 19.6%, respectively. MetS was positively associated with BMD in men, while in women it was negatively associated with BMD. Regarding the relationship between MetS components and BMD, we found that in women, waist circumference (WC) and systolic and diastolic blood pressure were negatively associated with BMD, while high-density lipoprotein cholesterol (HDL-C) was positively associated. In men, WC and fasting glucose were positively associated with BMD, while HDL-C was negatively associated. We also found that an increase in the number of MetS components resulted in a significantly increased positive association with BMD, both before and after adjusting for age, in men but not in women, revealing a gender difference in the correlation between MetS components and BMD.
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