Evidence map›Paper›PMID 28303376›Full record

ArticleNeuroradiology2017

Parkinson's disease: diagnostic utility of volumetric imaging.

Wei-Che Lin, Kun-Hsien Chou, Pei-Lin Lee, Nai-Wen Tsai, Hsiu-Ling Chen, Ai-Ling Hsu, Meng-Hsiang Chen, Yung-Cheng Huang, Ching-Po Lin, Cheng-Hsien Lu

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Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei-Che LinDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Kun-Hsien ChouBrain Research Center, National Yang-Ming University, Taipei, Taiwan.
Pei-Lin LeeDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan.
Nai-Wen TsaiDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung, Kaohsiung, Taiwan.
Hsiu-Ling ChenDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Ai-Ling HsuInstitute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
Meng-Hsiang ChenDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Yung-Cheng HuangDepartment of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Ching-Po LinBrain Research Center, National Yang-Ming University, Taipei, Taiwan.
Cheng-Hsien LuDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung, Kaohsiung, Taiwan. chlu99@ms44.url.com.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis paper aims to examine the effectiveness of structural imaging as an aid in the diagnosis of Parkinson's disease (PD).

methodsHigh-resolution T

resultsSmaller volume in susceptible regions is diagnostic for Parkinson's disease. Compared with the other two classifiers, the basal ganglion prior/data-driven hybrid classifier had the highest diagnostic reliability with a sensitivity of 74%, specificity of 75%, and accuracy of 74%. Furthermore, outcome measurement using this classifier was associated with disease severity.

conclusionsBrain structural volumetric analysis with multiple logistic regression modeling can be a complementary tool for diagnosing PD.

Indexed as

FemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedParkinson DiseaseProspective StudiesSensitivity and SpecificitySeverity of Illness IndexBrain volumeGray matterMovement disorderMRIParkinson’s disease

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.