SynthesisClinical rheumatology2017
The effect of balneotherapy on pain relief, stiffness, and physical function in patients with osteoarthritis of the knee: a meta-analysis.
Synthesis in Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Clinical efficacy of medical hydrology: an umbrella review.International journal of biometeorology · 2021Pooled it
- Pooled it
- Effects of balneotherapy and spa therapy on quality of life of patients with knee osteoarthritis: a systematic review and meta-analysis.Rheumatology international · 2018Pooled it
- The role of mineral elements and other chemical compounds used in balneology: data from double-blind randomized clinical trials.International journal of biometeorology · 2017Pooled it
- Effects of serial thermal brine hand baths on hand osteoarthritis: a randomized, double-blind, sham-controlled trial.European journal of physical and rehabilitation medicine · 2026Trial
- Comparison of outpatient and inpatient spa therapy in knee osteoarthritis.International journal of biometeorology · 2021Trial
- Balneotherapy for knee osteoarthritis in S. Jorge: a randomized controlled trial.International journal of biometeorology · 2020Trial
- Balneotherapy for musculoskeletal pain: does the mineral content matter?International journal of biometeorology · 2020Trial
- Effect of balneotherapy on pain and fatigue in elderly with knee osteoarthritis receiving physical therapy: a randomized trial.International journal of biometeorology · 2019Trial
- The effects of inpatient versus outpatient spa therapy on pain, anxiety, and quality of life in elderly patients with generalized osteoarthritis: a pilot study.International journal of biometeorology · 2018Trial
- Spa therapy adjunct to pharmacotherapy is beneficial in rheumatoid arthritis: a crossover randomized controlled trial.International journal of biometeorology · 2018Trial
- Impact of Comprehensive Health Resort Treatment on Insomnia and Quality of Life in Older Adults: A Pre-Experimental Study.Healthcare (Basel, Switzerland) · 2026Article
- Causal relationship between modifiable risk factors and knee osteoarthritis: a Mendelian randomization study.Frontiers in medicine · 2024Article
- Effect of Shi-Style Steaming and Bathing Decoction in Patients with Knee Osteoarthritis: Study Protocol for a Randomized Placebo-Controlled Trial.Journal of pain research · 2024Article
- Mechanism of Astragali Radix for the treatment of osteoarthritis: A study based on network pharmacology and molecular docking.Medicine · 2022Article
- The efficacy of balneotherapy, mud therapy and spa therapy in patients with osteoarthritis: an overview of reviews.International journal of biometeorology · 2021Review
- Non-Surgical Treatment of Knee Osteoarthritis: Multidisciplinary Italian Consensus on Best Practice.Therapeutics and clinical risk management · 2021Article
- A comprehensive analysis to understand the mechanism of action of balneotherapy: why, how, and where they can be used? Evidence from in vitro studies performed on human and animal samples.International journal of biometeorology · 2020Review
- Spa therapy and rehabilitation of musculoskeletal pathologies: a proposal for best practice in Italy.International journal of biometeorology · 2020Article
- Effects of Balneotherapy in Jeju Magma-Seawater on Knee Osteoarthritis Model.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This meta-analysis was performed to determine the effect of balneotherapy on relieving pain and stiffness and improving physical function, compared to controls, among patients with knee osteoarthritis. We searched electronic databases for eligible studies published from 2004 to December 31, 2016, with language restrictions of English or Japanese. We screened publications in Medline, Embase, Cochrane library, and the Japan Medical Abstracts Society Database using two approaches, MeSH terms and free words. Studies that examined the effect of balneotherapy for treating knee osteoarthritis of a ≥2-week duration were included. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were used as the outcome measure. A total of 102 publications were assessed according to the exclusion criteria of the study; eight clinical trial studies, which comprised a total of 359 cases and 375 controls, were included in this meta-analysis. The meta-analysis analyzed improvement in WOMAC score at the final follow-up visit, which varied from 2 to 12 months post-intervention. Our meta-analysis indicates that balneotherapy was clinically effective in relieving pain and stiffness, and improving function, as assessed by WOMAC score, compared to controls. However, there was high heterogeneity (88 to 93%). It is possible that balneotherapy may reduce pain and stiffness, and improve function, in individuals with knee osteoarthritis, although the quality of current publications contributes to the heterogeneity observed in this meta-analysis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.