Evidence map›Paper›PMID 28303276›Full record

ArticleJournal of biomechanical engineering2017

A Parameterized Ultrasound-Based Finite Element Analysis of the Mechanical Environment of Pregnancy.

Andrea R Westervelt, Michael Fernandez, Michael House, Joy Vink, Chia-Ling Nhan-Chang, Ronald Wapner, Kristin M Myers

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomechanical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Equilibrium Mechanical Properties of the Nonhuman Primate Cervix.Journal of biomechanical engineering · 2024
    Article
  7. [Prevention of Spontaneous Premature Birth With Cervical Pessary: A Single-Center Prospective Cohort Study].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Tissue Engineering for Cervical Function in Pregnancy.Current opinion in biomedical engineering · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Andrea R WesterveltDepartment of Mechanical Engineering, Columbia University, New York, NY 10027 e-mail: arw2181@columbia.edu.
Michael FernandezDepartment of Mechanical Engineering, Columbia University, New York, NY 10027 e-mail: mjf2152@columbia.edu.
Michael HouseDepartment of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA 02111 e-mail: mhouse@tuftsmedicalcenter.org.
Joy VinkDepartment of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032 e-mail: jyv2101@cumc.columbia.edu.
Chia-Ling Nhan-ChangDepartment of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032 e-mail: cn2281@cumc.columbia.edu.
Ronald WapnerDepartment of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032 e-mail: rw2181@cumc.columbia.edu.
Kristin M MyersMem. ASME Department of Mechanical Engineering, Columbia University, New York, NY 10027 e-mail: kmm2233@columbia.edu.
Columbia University · USColumbia University Irving Medical Center · USTufts Medical Center · US

Funding

A Computational Framework for the Clinical Evaluation of the Soft Tissue Mechanics in PregnancyR01HD091153 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MYERS, KRISTIN MARIE · 2017 to 2021
$1.6M
Evaluating the role of human cervical smooth muscle cells in normal and premature cervical remodelingK08HD088758 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VINK, JOY-SARAH · 2016 to 2020
$801k
EPA EP-C-15-002NICHD NIH HHS K08 HD088758NICHD NIH HHS R01 HD091153
6 · The paper itself

Abstract

Preterm birth is the leading cause of childhood mortality and can lead to health risks in survivors. The mechanical functions of the uterus, fetal membranes, and cervix have dynamic roles to protect the fetus during gestation. To understand their mechanical function and relation to preterm birth, we built a three-dimensional parameterized finite element model of pregnancy. This model is generated by an automated procedure that is informed by maternal ultrasound measurements. A baseline model at 25 weeks of gestation was characterized, and to visualize the impact of cervical structural parameters on tissue stretch, we evaluated the model sensitivity to (1) anterior uterocervical angle, (2) cervical length, (3) posterior cervical offset, and (4) cervical stiffness. We found that cervical tissue stretching is minimal when the cervical canal is aligned with the longitudinal uterine axis, and a softer cervix is more sensitive to changes in the geometric variables tested.

Indexed as

Finite Element AnalysisMechanical PhenomenaUltrasonographyAdultBiomechanical PhenomenaCervix UteriFemaleHumansPregnancyUterus

Identifiers

PMID28303276
PMCPMC7104753
OpenAlexW2596934581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.