Evidence map›Paper›PMID 28302905›Full record

ArticleJournal of cell science2017

Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in

Margarethakay Scavello, Alexandra R Petlick, Ramya Ramesh, Valery F Thompson, Pouya Lotfi, Pascale G Charest

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Evaluating the Activity of Ras/Rap GTPases in Dictyostelium.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  3. Proximity Protein Labeling InJournal of biological methods · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Eat Prey, Live:Frontiers in immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Margarethakay ScavelloDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA.
Alexandra R PetlickDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA.ORCID 0000-0002-9908-8457
Ramya RameshDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA.
Valery F ThompsonDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA.
Pouya LotfiDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA.
Pascale G CharestDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721-0088, USA pcharest@email.arizona.edu.ORCID 0000-0002-2395-5294
University of Arizona · US

Funding

SIGNALLING PROCESSES IN DICTYOSTELIUMR01GM037830 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRTEL, RICHARD A · 1986 to 2015
$8.5M
CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
EPA EP-C-15-024NIGMS NIH HHS R01 GM037830NIGMS NIH HHS T32 GM008804
6 · The paper itself

Abstract

Efficient directed migration requires tight regulation of chemoattractant signal transduction pathways in both space and time, but the mechanisms involved in such regulation are not well understood. Here, we investigated the role of protein kinase A (PKA) in controlling signaling of the chemoattractant cAMP in

Indexed as

Signal TransductionActinsChemotactic FactorsChemotaxisCyclic AMP-Dependent Protein KinasesDictyosteliumMechanistic Target of Rapamycin Complex 2Models, BiologicalMyosinsPhenotypeProtozoan Proteinsrap1 GTP-Binding Proteinsras ProteinsTime FactorsActinsChemotactic FactorsCyclic AMP-Dependent Protein KinasesMechanistic Target of Rapamycin Complex 2MyosinsProtozoan Proteinsrap1 GTP-Binding Proteinsras ProteinsChemotactic signalingChemotaxisDirectional sensingMigrationNegative feedbackPKA

Identifiers

PMID28302905
PMCPMC5450229
OpenAlexW2596276903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.