ArticleDeutsches Arzteblatt international2017
Lower Limb Amputation in Germany.
Article in Deutsches Arzteblatt international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Understanding variations in reported epidemiology of major lower extremity amputation in the UK: a systematic review.BMJ open · 2021Pooled it
- Effect of Cold Atmospheric Plasma Therapy vs Standard Therapy Placebo on Wound Healing in Patients With Diabetic Foot Ulcers: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Targeted muscle reinnervation surgery modulates apoptosis and synaptic plasticity to improve motor function following tibial nerve injury in rats.Annals of medicine · 2026Article
- Sex-Specific Differences in Patients with Sarcopenia and Peripheral Artery Disease.Muscles (Basel, Switzerland) · 2026Article
- Engineering-based statistical analysis of amputation prevalence and the impact of contributing factors in 4 Iraqi cities (1980-2024).Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- The Changing Rates of Lower-Limb Amputations in Germany: An Analysis of Data from the Federal Statistical Office, 2005–2023.Deutsches Arzteblatt international · 2025Article
- Epidemiology and the Medical Burden of Diabetic Foot Ulcers Especially in Patients With Infection-A Population-Based Analysis From Germany.International wound journal · 2025Article
- [Major amputations of the lower extremity].Unfallchirurgie (Heidelberg, Germany) · 2025Review
- FHIR-standardized data collection on the clinical rehabilitation pathway of trans-femoral amputation patients.Scientific data · 2024Article
- The Incidence and Outcomes of Major Limb Amputation in New Zealand from 2010 to 2021.Journal of clinical medicine · 2024Article
- Five-Year Trends of Vascular Disease-Related Amputations in Romania: A Retrospective Database Study.Journal of clinical medicine · 2024Article
- Peripheral Arterial Disease and the Diabetic Foot Syndrome: Neuropathy Makes the Difference! A Narrative Review.Journal of clinical medicine · 2024Review
- Can Early Post-Operative Scoring of Non-Traumatic Amputees Decrease Rates of Revision Surgery?Medicina (Kaunas, Lithuania) · 2024Article
- Lower Extremity Amputation and Peripheral Revascularisation Rates in Romania and Their Relationship with Comorbidities and Vascular Care.Journal of clinical medicine · 2023Article
- Comorbidity and risk factors of subsequent lower extremity amputation in patients diagnosed with diabetes in Saskatchewan, Canada.Chronic illness · 2023Article
- [Motion analysis in lower limb exoprosthetics-possibilities and limitations].Orthopadie (Heidelberg, Germany) · 2023Review
- Incidence of Lower Extremity Amputation in Romania: A Nationwide 5-Year Cohort Study, 2015-2019.Medicina (Kaunas, Lithuania) · 2023Article
- Patient-Specific Guides for Accurate and Precise Positioning of Osseointegrated Implants in Transfemoral Amputations: A Proof-of-Concept In Vitro Study.Medicina (Kaunas, Lithuania) · 2023Article
- Salami-Tactics: when is it time for a major cut after multiple minor amputations?Archives of orthopaedic and trauma surgery · 2023Article
- Demographics and Etiology for Lower Extremity Amputations-Experiences of an University Orthopaedic Center in Germany.Medicina (Kaunas, Lithuania) · 2023Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeclining amputation rates have been reported in multiple countries in recent years. It is not yet known whether amputation rates have declined in Germany as well.
methodsOn the basis of DRG (diagnosis-related group) data, we received a list from the German Federal Statistical Office of all major and minor amputations documented in German hospitals from 2005 to 2014. Changes over this period were studied with linear regression.
resultsThe absolute number of amputations per year in Germany rose slightly from 55 689 in 2005 to 57 637 (+3.5%) in 2014. After the exclusion of cases in which the main diagnosis was trauma, intoxication, musculoskeletal disease, diseases of the skin and subcutaneous tissue, or neoplasia, the corresponding numbers were 48 043 in 2005 and 48 561 in 2014 (+1.1%). The age-adjusted rate of major amputations per 100 000 persons per year fell from 23.3 to 16.1 (-30.9%), while the rate of minor amputations rose from 35.0 to 43.9 (+25.4%). The percentage of major amputations that took place in patients with diabetes mellitus as the main diagnosis or a side diagnosis declined from 70.2% to 63.7%. For all of these changes, p <0.0001.
conclusionFrom 2005 to 2014, the major amputation rate fell by 30.9% while the minor amputation rate rose by 25.4%. The goal of lowering amputation rates still further will be best served not only by applying the recognized preventive measures in patients with foot lesions, but also by further research into the causes of the recent changes in amputation numbers. Prospective registries will be needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.