Evidence map›Paper›PMID 28302123›Full record

ArticleLipids in health and disease2017

Relationship between non-high-density lipoprotein cholesterol and carotid atherosclerosis in normotensive and euglycemic Chinese middle-aged and elderly adults.

Hui Ma, Huandong Lin, Yu Hu, Xiaoming Li, Wanyuan He, Xuejuan Jin, Jian Gao, Naiqing Zhao, Boshen Pan, Xin Gao

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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  7. The association between screen time and cardiometabolic risk in young children.The international journal of behavioral nutrition and physical activity · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hui MaDepartment of Geriatrics, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Huandong LinDepartment of Endocrinology and Metabolism, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Yu HuDepartment of Geriatrics, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Xiaoming LiDepartment of Endocrinology and Metabolism, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Wanyuan HeDepartment of Ultrasonography, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Xuejuan JinClinical Epidemiology Center, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Jian GaoDepartment of Clinical Nutrition, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China.
Naiqing ZhaoDepartment of Biostatistics, College of Public Health, Fudan University, Shanghai, 200032, China.
Boshen PanDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, 20032, China.
Xin GaoDepartment of Endocrinology and Metabolism, Zhong Shan Hospital, Fudan University, Shanghai, 200032, China. zhongshan_endo@126.com.
Fudan University · CNSun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigate whether non-high-density lipoprotein cholesterol (non-HDL-C) provides a better estimate of cardiovascular risk than other lipid profiles in normotensive and euglycemic middle-aged and elderly adults.

methodsA total of 512 males and 958 females were enrolled from the Changfeng Study. A standard interview, anthropometric measurements and laboratory analyses were performed for each participant. Bilateral carotid intima-media thicknesses (CIMTs) were measured using ultrasonography, and the presence of carotid plaques was assessed.

resultsThe mean values of non-HDL-C were 3.4 ± 0.8 mmol/l and 3.6 ± 0.9 mmol/l for male and female subjects, respectively. Compared with female subjects with non-HDL-C in the first quartile, female subjects with non-HDL-C in the fourth quartile had 1.317-fold increased risks for carotid plaques after adjusting for conventional cardiovascular disease (CVD) risk factors and increasing quartiles of all lipid levels. Non-HDL-C was positively associated with the CIMT after adjusting for CVD risk factors in female subjects (β = 0.062, P = 0.034).

conclusionsThese results suggest that non-HDL-C is independently associated with carotid atherosclerosis in normotensive and euglycemic females.

Indexed as

AgedAsian PeopleAtherosclerosisBlood GlucoseBlood PressureCarotid Artery DiseasesCarotid Intima-Media ThicknessChinaCholesterol, HDLCholesterol, LDLCross-Sectional StudiesFemaleHumansMaleMiddle AgedPlaque, AtheroscleroticBlood GlucoseCholesterol, HDLCholesterol, LDLCarotid atherosclerosisCarotid intima-media thickness (CIMT)Carotid plaqueNon-HDL-C

Identifiers

PMID28302123
PMCPMC5356399
OpenAlexW2595115777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.