ArticleBMC psychiatry2017
Insomnia symptoms as a cause of type 2 diabetes Incidence: a 20 year cohort study.
Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Dietary patterns and insomnia symptoms: A systematic review and meta-analysis.Sleep medicine reviews · 2024Pooled it
- Impact of transdermal trigeminal electrical neuromodulation on subjective and objective sleep parameters in patients with insomnia: a pilot study.Sleep & breathing = Schlaf & Atmung · 2022Trial
- Effect of Acupuncture Cooperated with Low-frequency Repetitive Transcranial Magnetic Stimulation on Chronic Insomnia: A Randomized Clinical Trial.Current medical science · 2018Trial
- Psychological Resilience in Individuals with Type 2 Diabetes Mellitus in Jordan Is Associated with Insomnia Severity: A Cross-Sectional Analysis.Journal of clinical medicine · 2026Article
- The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study.Scientific reports · 2024Article
- Sleeplessness and incident diabetes above the Arctic circle: a secondary analysis of cohort data from the Tromsø Study.BMJ public health · 2024Article
- Chronic insomnia, high trait anxiety and their comorbidity as risk factors for incident type 2 diabetes mellitus.Scientific reports · 2024Article
- Clinical Spectrum and Trajectory of Innovative Therapeutic Interventions for Insomnia: A Perspective.Aging and disease · 2023Article
- Causal association between sleep traits and the risk of coronary artery disease in patients with diabetes.Frontiers in cardiovascular medicine · 2023Article
- Insomnia symptoms are associated with an increased risk of type 2 diabetes mellitus among adults aged 50 and older.Sleep & breathing = Schlaf & Atmung · 2022Article
- Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study.Diabetes care · 2022Article
- Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data.PLoS genetics · 2021Article
- Chronobiology and the case for sleep health interventions in the community.Singapore medical journal · 2021Article
- Insomnia and type 2 diabetes mellitus: a risk assessment.Sleep & breathing = Schlaf & Atmung · 2021Article
- Oral Antidiabetics and Sleep Among Type 2 Diabetes Patients: Data From the UK Biobank.Frontiers in endocrinology · 2021Article
- Relationship between sleep disturbances, lipid profile and insulin sensitivity in type 1 diabetic patients: a cross-sectional study.Archives of endocrinology and metabolism · 2020Article
- Association Between Childhood Behavioral Problems and Insomnia Symptoms in Adulthood.JAMA network open · 2019Article
- Association between insomnia and type 2 diabetes mellitus in Han Chinese individuals in Shandong Province, China.Sleep & breathing = Schlaf & Atmung · 2019Article
- The Play of Genes and Non-genetic Factors on Type 2 Diabetes.Frontiers in public health · 2019Review
- Association between Sedative-hypnotics and Subsequent Cancer in Patients with and without Insomnia: A 14-year Follow-up Study in Taiwan.Journal of Cancer · 2019Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundInsomnia symptoms are associated with type 2 diabetes incidence but are also associated with a range of potential time-varying covariates which may confound and/or mediate associations. We aimed to assess whether cumulative exposure to insomnia symptoms has a causal effect on type 2 diabetes incidence.
methodsA prospective cohort study in the West of Scotland, following respondents for 20 years from age 36. 996 respondents were free of diabetes at baseline and had valid data from up to four follow-up visits. Type 2 diabetes was assessed at the final visit by self-report, taking diabetic medication, or blood-test (HbA
resultsTraditional regression yielded an odds ratio (OR) of 1.34 (95% CI: 1.06-1.70) for type 2 diabetes incidence for each additional survey wave in which insomnia was reported. Marginal structural models adjusted for prior covariates (assuming concurrently measured covariates were potential mediators), reduced this OR to 1.20 (95% CI: 0.98-1.46), and when concurrent covariates were also included (viewing them as potential confounders) this dropped further to 1.08 (95% CI: 0.85-1.37).
conclusionsThe association between cumulative experience of insomnia and type 2 diabetes incidence appeared confounded. Evidence for a residual causal effect depended on assumptions as to whether concurrently measured covariates were confounders or mediators.
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