ArticlePharmaceutical biology2017
Unlocking the in vitro anti-inflammatory and antidiabetic potential of Polygonum maritimum.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 48 citations in OpenAlex.
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- Bioactivity and Chemical Profiling of the Sea-Ice MicroalgaBiomolecules · 2025Article
- Natural solutions for diabetes: the therapeutic potential of plants and mushrooms.Frontiers in nutrition · 2025Review
- The genusHeliyon · 2024Review
- Phytochemical Profiles and Biological Activities ofMolecules (Basel, Switzerland) · 2024Review
- Anti-diabetic and anti-inflammatory bioactive hits fromFrontiers in pharmacology · 2024Article
- Harnessing the Bioactive Potential ofPlants (Basel, Switzerland) · 2023Article
- Biosynthesis and Characterization of Silver Nanoparticles UsingMolecules (Basel, Switzerland) · 2023Article
- Antigenotoxic properties of the halophyte Polygonum maritimum L. highlight its potential to mitigate oxidative stress-related damage.Scientific reports · 2023Article
- Metabolomic Profile ofMetabolites · 2023Article
- Application ofPlants (Basel, Switzerland) · 2022Review
- The Medicinal HalophytePlants (Basel, Switzerland) · 2022Article
- A first approach for the micropropagation of the medicinal halophyteFrontiers in plant science · 2022Article
- Greener Is Better: First Approach for the Use of Natural Deep Eutectic Solvents (NADES) to Extract Antioxidants from the Medicinal HalophyteMolecules (Basel, Switzerland) · 2021Article
- An Update on Phytochemicals and Pharmacological Activities of the GenusMolecules (Basel, Switzerland) · 2021Review
- Antidiabetic Potential of Medicinal Plants and Their Active Components.Biomolecules · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextSeveral Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes.
objectiveEvaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and dichloromethane extracts of leaves and roots of the halophyte Polygonum maritimum L. MATERIAL AND
methodsAntioxidant activity was determined (up to 1 mg/mL) as radical-scavenging activity (RSA) of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), copper (CCA) and iron (ICA) chelating activities and iron reducing power (FRAP). NO production was measured in lipopolysaccharide (LPS)-stimulated macrophages for 24 h at concentrations up to 100 μg/mL and antidiabetic potential was assessed by α-amylase and α-glucosidase inhibition (up to 10 mg/mL) assays. The phytochemical composition of the extracts was determined by gas chromatography-mass spectrometry (GC-MS).
resultsThe methanol leaf extract had the highest activity against DPPH• (IC
conclusionsOur findings suggest P. maritimum as a source of high-value health promoting commodities for alleviating symptoms associated with oxidative and inflammatory diseases, including diabetes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.