Evidence map›Paper›PMID 28301838›Full record

ReviewAnnals of nutrition & metabolism2017

The Interplay between Maternal Nutrition and Stress during Pregnancy: Issues and Considerations.

Karen L Lindsay, Claudia Buss, Pathik D Wadhwa, Sonja Entringer

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Annals of nutrition & metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03278392 (Prenatal Emotion-Diet Interactions and the Metabolic Response), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03278392 nacompletednot on this map

Prenatal Emotion-Diet Interactions and the Metabolic Response

TypeinterventionalSponsorUniversity of California, IrvineRan2017 to 2021Enrolled38ConditionsPregnancy Related, Stress, Psychological, Glucose Intolerance During PregnancyArmsTrier Social Stress Test, Placebo Non-stress task
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. African American Food Environments and Anti-Inflammatory Intake in Pregnancy.International journal of environmental research and public health · 2026
    Article
  7. Validation of the Greek Version of Tilburg Pregnancy Distress Scale (TPDS).Advances in experimental medicine and biology · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karen L LindsayUC Irvine Development, Health and Disease Research Program, University of California, Irvine, CA, USA.
Claudia Buss
Pathik D Wadhwa
Sonja Entringer
University of California, Irvine · US

Funding

Maternal Acculturation in Pregnancy and Infant Adiposity in Mexican AmericansR01MD010738 · NIMHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ENTRINGER, SONJA, WADHWA, PATHIK D · 2016 to 2020
$3.6M
EMA Assessment of Biobehavioral Processes in Human PregnancyR01HD060628 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WADHWA, PATHIK D · 2010 to 2014
$3.4M
Prenatal stress biology, infant body composition and obesity riskR01HD065825 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ENTRINGER, SONJA, WADHWA, PATHIK D · 2010 to 2014
$2.2M
Prenatal diet-stress interactions and the maternal metabolic response in human pregnancyK99HD096109 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI LINDSAY, KAREN · 2018 to 2019
$188k
NICHD NIH HHS K99 HD096109NICHD NIH HHS R01 HD060628NICHD NIH HHS R01 HD065825NIMHD NIH HHS R01 MD010738
6 · The paper itself

Abstract

backgroundSeveral studies about humans and animals have separately examined the effects of prenatal nutrition and stress on fetal development, pregnancy, and birth outcomes, and subsequent child health and disease risk. Although substantial evidence from non-pregnant literature supports the presence of bidirectional interactions between nutrition and stress at various psychological, behavioral, and physiological levels, such interaction effects have not yet been systematically examined in the context of pregnancy. SUMMARY: This paper discusses the multifaceted and multilevel relationship between nutrition and stress. It then reviews the currently available observational and experimental evidence in animals and humans regarding the interplay between maternal psychosocial stress, dietary intake, and nutritional state during pregnancy, and implications for maternal and child health-related outcomes. Key Messages: During pregnancy, maternal psychosocial stress, dietary behavior, and nutritional state likely regulate and counter-regulate one another. Emerging evidence suggests that omega-3 fatty acids may attenuate maternal psychosocial stress, and that high maternal pre-pregnancy body mass index exacerbates unhealthy dietary behaviors under high-stress conditions. Longitudinal studies are warranted in order to understand the interplay between prenatal psychosocial stress, diet, and stress- and nutrition-related biomarkers to obtain further insight and inform the development and design of future, more effective intervention trials for improved maternal and child health outcomes.

Indexed as

Maternal Nutritional Physiological PhenomenaAdultAnimalsBody Mass IndexEatingFatty Acids, Omega-3Feeding BehaviorFemaleFetal DevelopmentHumansNutritional StatusPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsStress, PsychologicalFatty Acids, Omega-3AnxietyDepressionDietary intakesFetal programmingNutritionPerceived stressPregnancyPsychosocial states

Identifiers

PMID28301838
PMCPMC6358211
OpenAlexW2597091415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.