Evidence map›Paper›PMID 28301586›Full record

ArticlePloS one2017

Influence of early neurological complications on clinical outcome following lung transplant.

Josep Gamez, Maria Salvado, Alejandro Martinez-de La Ossa, Maria Deu, Laura Romero, Antonio Roman, Judith Sacanell, Cesar Laborda, Isabel Rochera, Miriam Nadal and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Impact of Post-Operative Phrenic Nerve Dysfunction on Lung Function Parameters and Long-Term Outcomes After Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  4. Diaphragmatic palsy following lung transplantation.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  5. Non-pulmonary complications after lung transplantation: Part I.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Josep GamezNeurology Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-3127-7486
Maria SalvadoNeurology Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain.
Alejandro Martinez-de La OssaDepartment of Neurophysiology, Vall d'Hebron University Hospital, Autonomous University of Barcelona, Barcelona, Spain.
Maria DeuDepartment of Thoracic Surgery, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Laura RomeroDepartment of Thoracic Surgery, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Antonio RomanDepartment of Pulmonology, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Judith SacanellCritical Care Department, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Cesar LabordaCritical Care Department, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Isabel RocheraDepartment of Anesthesiology, Vall d'Hebron University Hospital, Barcelona, Spain.
Miriam NadalDepartment of Anesthesiology, Vall d'Hebron University Hospital, Barcelona, Spain.
Francesc CarmonaDepartment of Statistics, University of Barcelona, Barcelona, Spain.
Estevo SantamarinaNeurology Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain.
Nuria RaguerDepartment of Neurophysiology, Vall d'Hebron University Hospital, Autonomous University of Barcelona, Barcelona, Spain.
Merce CanelaDepartment of Thoracic Surgery, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Joan SoléDepartment of Thoracic Surgery, Lung Transplant Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESUniversitat Autònoma de Barcelona · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurological complications after lung transplantation are common. The full spectrum of neurological complications and their impact on clinical outcomes has not been extensively studied.

methodsWe investigated the neurological incidence of complications, categorized according to whether they affected the central, peripheral or autonomic nervous systems, in a series of 109 patients undergoing lung transplantation at our center between January 1 2013 and December 31 2014.

resultsFifty-one patients (46.8%) presented at least one neurological complication. Critical illness polyneuropathy-myopathy (31 cases) and phrenic nerve injury (26 cases) were the two most prevalent complications. These two neuromuscular complications lengthened hospital stays by a median period of 35.5 and 32.5 days respectively. However, neurological complications did not affect patients' survival.

conclusionsThe real incidence of neurological complications among lung transplant recipients is probably underestimated. They usually appear in the first two months after surgery. Despite not affecting mortality, they do affect the mean length of hospital stay, and especially the time spent in the Intensive Care Unit. We found no risk factor for neurological complications except for long operating times, ischemic time and need for transfusion. It is necessary to develop programs for the prevention and early recognition of these complications, and the prevention of their precipitant and risk factors.

Indexed as

AdolescentAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornLung TransplantationMaleMiddle AgedPolyneuropathiesRetrospective StudiesSurvival AnalysisYoung Adult

Identifiers

PMID28301586
PMCPMC5354450
OpenAlexW2595570788

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.