ArticlePloS one2017
A screening questionnaire for convulsive seizures: A three-stage field-validation in rural Bolivia.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 23 citations in OpenAlex.
- Effects of an Educational Comic Book on Knowledge, Attitudes, and Practices Regarding Epilepsy among Adolescents in Quito, Ecuador.Neuroepidemiology · 2026Article
- Unmet needs of women with epilepsy living in rural low- and middle-income countries: The experience of the Bolivian Chaco.Epilepsia open · 2025Article
- The Urban-Rural Divide in Neurocritical Care in Low-Income and Middle-Income Countries.Neurocritical care · 2024Article
- Epilepsy and neurocysticercosis in rural areas of the Bolivian Chaco: What has changed during the last 30 years?Epilepsia open · 2024Article
- Prevalence of epilepsy in the rural area of the Bolivian Gran Chaco: Usefulness of telemedicine and impact of awareness campaigns.Epilepsia open · 2023Article
- Community-level prevalence of epilepsy and of neurocysticercosis among people with epilepsy in the Balaka district of Malawi: A cross-sectional study.PLoS neglected tropical diseases · 2022Article
- Lifetime prevalence of epilepsy in urban Tanzania - A door-to-door random cluster survey.eNeurologicalSci · 2021Article
- The impact of COVID-19 pandemic on frail health systems of low- and middle-income countries: The case of epilepsy in the rural areas of the Bolivian Chaco.Epilepsy & behavior : E&B · 2021Article
- Improving Patient-Centered Communication about Sudden Unexpected Death in Epilepsy through Computerized Clinical Decision Support.Applied clinical informatics · 2021Article
- Calibration of the Epilepsy Questionnaire for Use in a Low-Resource Setting.Journal of environmental and public health · 2020Article
- A screening questionnaire for generalized tonic-clonic seizures: Hospital-based validation vs field-validation method.Epilepsia open · 2019Article
- Comprehensive management of epilepsy in onchocerciasis-endemic areas: lessons learnt from community-based surveys.Infectious diseases of poverty · 2019Review
- The impact of imperfect screening tools on measuring the prevalence of epilepsy and headaches in Burkina Faso.PLoS neglected tropical diseases · 2019Article
- Treating People With Epilepsy in Rural Low-Income Countries Is Feasible. Observations and Reflections From a "Real Life Experience" After a Long Lasting Intervention in the Rural Chaco.Frontiers in neurology · 2018Article
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Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEpilepsy is one of the most common neurological diseases in Latin American Countries (LAC) and epilepsy associated with convulsive seizures is the most frequent type. Therefore, the detection of convulsive seizures is a priority, but a validated Spanish-language screening tool to detect convulsive seizures is not available. We performed a field validation to evaluate the accuracy of a Spanish-language questionnaire to detect convulsive seizures in rural Bolivia using a three-stage design. The questionnaire was also administered face-to-face, using a two-stage design, to evaluate the difference in accuracy.
methodsThe study was carried out in the rural communities of the Gran Chaco region. The questionnaire consists of a single screening question directed toward the householders and a confirmatory section administered face-to-face to the index case. Positive subjects underwent a neurological examination to detect false positive and true positive subjects. To estimate the proportion of false negative, a random sample of about 20% of the screened negative underwent a neurological evaluation.
results792 householders have been interviewed representing a population of 3,562 subjects (52.2% men; mean age 24.5 ± 19.7 years). We found a sensitivity of 76.3% (95% CI 59.8-88.6) with a specificity of 99.6% (95% CI 99.4-99.8). The two-stage design showed only a slightly higher sensitivity respect to the three-stage design.
conclusionOur screening tool shows a good accuracy and can be easily used by trained health workers to quickly screen the population of the rural communities of LAC through the householders using a three-stage design.
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