ArticlePloS one2017
Association of lower urinary tract syndrome with peripheral arterial occlusive disease.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Therapeutic potential of MitoQ, a mitochondria-targeted antioxidant, in age-related physiological dysfunction.GeroScience · 2026Review
- Acute dual therapeutic effects of the BKCa channel opener LDD175 on erectile dysfunction and lower urinary tract symptoms in chronic pelvic ischemia: a preliminary study.Asian journal of andrology · 2025Article
- Characterizing the spectrum of bladder health and lower urinary tract symptoms among men: Results from the CARDIA study.Neurourology and urodynamics · 2024Article
- Article
- Risk Factors for Postoperative Urinary Retention Following Lumbar Spine Surgery: A Review of Current Literature and Meta-Analysis.Global spine journal · 2023Review
- Molecular Regulation of Concomitant Lower Urinary Tract Symptoms and Erectile Dysfunction in Pelvic Ischemia.International journal of molecular sciences · 2022Review
- Long-Term Exposures to Air Pollutants and Risk of Peripheral Arterial Occlusive Disease: A Nationwide Cohort Study in Taiwan.Frontiers in cardiovascular medicine · 2022Article
- Cellular Stress and Molecular Responses in Bladder Ischemia.International journal of molecular sciences · 2021Review
- Impairment of AMPK-α2 augments detrusor contractions in bladder ischemia.Investigative and clinical urology · 2021Article
- Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia.Drugs & aging · 2021Article
- Phases of decompensation during acute ischemia demonstrated in anTranslational andrology and urology · 2020Article
- Increased One-Year Recurrent Ischemic Stroke after First-Ever Ischemic Stroke in Males with Benign Prostatic Hyperplasia.International journal of environmental research and public health · 2020Article
- Applying concepts of life course theory and life course epidemiology to the study of bladder health and lower urinary tract symptoms among girls and women.Neurourology and urodynamics · 2020Article
- Regulation of Cellular Stress Signaling in Bladder Ischemia.Research and reports in urology · 2020Article
- Bladder attack: transient bladder ischemia leads to a reversible decrease in detrusor compliance.Translational andrology and urology · 2019Article
- Antimuscarinic use and discontinuation in an older adult population.Archives of gerontology and geriatricsArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe atherosclerosis may lead to chronic bladder ischemia, eventually resulting in lower urinary tract syndrome (LUTS), and peripheral arterial occlusive disease (PAOD). We investigated the association of LUTS with PAOD.
methodsThis nationwide population-based cohort study was based on data from the Taiwan National Health Insurance Database from 2000 to 2010; follow-up lasted until the end of 2011. We identified patients with newly diagnosed LUTS by using International Classification of Diseases, Ninth Revision, Clinical Modification codes.
resultsIn total, 36,042 and 36,042 patients were enrolled in LUTS and non-LUTS cohorts, respectively. After adjustment for age, sex, and comorbidities, the risk of subsequent PAOD was 1.36-fold higher [95% confidence interval (CI) = 1.26-1.46] in the LUTS cohort than in the non-LUTS cohort. The adjusted risk of PAOD was the highest in patients with LUTS without any comorbidity [adjusted hazard ratio (aHR) = 1.93, 95% CI = 1.54-2.41]. The age-specific relative risk of PAOD was significantly higher in all age groups, particularly in those aged <49 years (aHR = 1.80, 95% CI = 1.39-2.34], in the LUTS cohort than in the non-LUTS cohort.
conclusionLUTS is a risk factor for PAOD. Physicians should consider the possibility of underlying PAOD in patients with LUTS aged <49 years and without cardiovascular comorbidities. Additional studies developing strategies for decreasing the risk of PAOD are warranted.
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