Evidence map›Paper›PMID 28300773›Full record

ReviewNutrients2017

The Low FODMAP Diet: Many Question Marks for a Catchy Acronym.

Giulia Catassi, Elena Lionetti, Simona Gatti, Carlo Catassi

Abstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. The role of diet in the pathophysiology and management of irritable bowel syndrome.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Review
  18. Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track.International journal of environmental research and public health · 2020
    Review
  19. Article
  20. FODMAP Intake in Spanish Population: Open Approach for Risk Assessment.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giulia CatassiDepartment of Pediatrics, Università Politecnica delle Marche, Via F. Corridoni 11, 60123 Ancona, Italy. giulia.catassi@gmail.com.
Elena LionettiDepartment of Pediatrics, Università Politecnica delle Marche, Via F. Corridoni 11, 60123 Ancona, Italy. mariaelenalionetti@gmail.com.
Simona GattiDepartment of Pediatrics, Università Politecnica delle Marche, Via F. Corridoni 11, 60123 Ancona, Italy. simona.gatti@hotmail.it.
Carlo CatassiDepartment of Pediatrics, Università Politecnica delle Marche, Via F. Corridoni 11, 60123 Ancona, Italy. c.catassi@univpm.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FODMAP, "Fermentable Oligo-, Di- and Mono-saccharides And Polyols", is a heterogeneous group of highly fermentable but poorly absorbed short-chain carbohydrates and polyols. Dietary FODMAPs might exacerbate intestinal symptoms by increasing small intestinal water volume, colonic gas production, and intestinal motility. In recent years the low-FODMAP diet for treatment of irritable bowel syndrome (IBS) has gained increasing popularity. In the present review we aim to summarize the physiological, clinical, and nutritional issues, suggesting caution in the prolonged use of this dietary treatment on the basis of the existing literature. The criteria for inclusion in the FODMAPs list are not fully defined. Although the low-FODMAP diet can have a positive impact on the symptoms of IBS, particularly bloating and diarrhea, the quality of the evidence is lower than optimal, due to frequent methodological flaws, particularly lack of a proper control group and/or lack of blinding. In particular, it remains to be proven whether this regimen is superior to conventional IBS diets. The drastic reduction of FODMAP intake has physiological consequences, e.g., on the intestinal microbiome and colonocyte metabolism, which are still poorly understood. A low-FODMAP diet imposes an important restriction of dietary choices due to the elimination of some staple foods, such as wheat derivatives, lactose-containing dairy products, many vegetables and pulses, and several types of fruits. For this reason, patients may be at risk of reduced intake of fiber, calcium, iron, zinc, folate, B and D vitamins, and natural antioxidants. The nutritional risk of the low-FODMAP diet may be higher in persons with limited access to the expensive, alternative dietary items included in the low-FODMAP diet.

Indexed as

DietDiarrheaFermentationFood HandlingFood PreferencesHumansIrritable Bowel SyndromeMicronutrientsMonosaccharidesOligosaccharidesPolymersRandomized Controlled Trials as TopicMicronutrientsMonosaccharidesOligosaccharidesPolymerspolyolfermentable sugarsirritable bowel syndromelow-FODMAP dietnon-celiac gluten sensitivitynutritional riskpolyols

Identifiers

PMID28300773
PMCPMC5372955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.