Evidence map›Paper›PMID 28300293›Full record

ArticleClinical cardiology2017

Coronary artery calcification is common on nongated chest computed tomography imaging.

Revathi Balakrishnan, Brian Nguyen, Roy Raad, Robert Donnino, David P Naidich, Jill E Jacobs, Harmony R Reynolds

Abstract read
In one paragraph

Article in Clinical cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  6. A missed opportunity: Incidental coronary artery calcification prior to acute coronary syndrome.International journal of cardiology. Heart & vasculature · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Revathi BalakrishnanCardiovascular Clinical Research Center, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York.
Brian NguyenCardiovascular Clinical Research Center, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York.
Roy RaadDepartment of Radiology, New York University School of Medicine, New York, New York.
Robert DonninoCardiovascular Clinical Research Center, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York.
David P NaidichDepartment of Radiology, New York University School of Medicine, New York, New York.
Jill E JacobsDepartment of Radiology, New York University School of Medicine, New York, New York.
Harmony R ReynoldsDepartment of Radiology, New York University School of Medicine, New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery calcification as assessed by computed tomography (CT) is a validated predictor of cardiovascular risk, whether identified on a dedicated cardiac study or on a routine non-gated chest CT. The prevalence of incidentally detected coronary artery calcification on non-gated chest CT imaging and consistency of reporting have not been well characterized. HYPOTHESIS: Coronary calcification is present on chest CT in some patients not taking statin therapy and may be under-reported.

methodsNon-gated chest CT images dated 1/1/2012 to 1/1/2013 were retrospectively reviewed. Demographics and medical history were obtained from charts. Patients with known history of coronary revascularization and/or pacemaker/defibrillator were excluded. Two independent readers with cardiac CT expertise evaluated images for the presence and anatomical distribution of any coronary calcification, blinded to all clinical information including CT reports. Original clinical CT reports were subsequently reviewed.

resultsCoronary calcification was identified in 204/304 (68%) chest CTs. Patients with calcification were older and had more hyperlipidemia, smoking history, and known coronary artery disease. Of patients with calcification, 43% were on aspirin and 62% were on statin medication at the time of CT. Coronary calcification was identified in 69% of reports when present.

conclusionsA high prevalence of coronary calcification was found in non-gated chest CT scans performed for non-cardiac indications. In one-third, coronary calcification was not mentioned in the clinical report when actually present. In this population of patients with cardiac risk factors, standard reporting of the presence of coronary calcification may provide an opportunity for risk factor modification.

Indexed as

AdultAgedAged, 80 and overCoronary Artery DiseaseCoronary VesselsFemaleHumansIncidental FindingsMaleMiddle AgedRadiography, ThoracicReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedVascular Calcificationcomputed tomography < Imagingcoronary artery diseasecoronary calcificationGeneral clinical cardiology/adultImagingPreventive cardiology

Identifiers

PMID28300293
PMCPMC6490415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.