Evidence map›Paper›PMID 28300193›Full record

ArticleScientific reports2017

Interplay of myosin phosphatase and protein phosphatase-2A in the regulation of endothelial nitric-oxide synthase phosphorylation and nitric oxide production.

Róbert Bátori, Bálint Bécsi, Dénes Nagy, Zoltán Kónya, Csaba Hegedűs, Zsuzsanna Bordán, Alexander Verin, Beáta Lontay, Ferenc Erdődi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  12. SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Róbert BátoriDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Bálint BécsiDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Dénes NagyDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Zoltán KónyaDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Csaba HegedűsDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Zsuzsanna BordánVascular Biology Center, Division of Pulmonary Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Alexander VerinVascular Biology Center, Division of Pulmonary Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Beáta LontayDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
Ferenc ErdődiDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.
University of Debrecen · HUAugusta University · US

Funding

Therapeutic Mechanisms of RhoA Inhibition In Acute Lung InjuryP01HL101902 · NHLBI · AUGUSTA UNIVERSITY · PI BLACK, STEPHEN M · 2011 to 2016
$11.2M
NHLBI NIH HHS P01 HL101902
6 · The paper itself

Abstract

The inhibitory phosphorylation of endothelial nitric oxide (NO) synthase (eNOS) at Thr497 (eNOS

Indexed as

AnimalsCatechinCattleCell LineElectric ImpedanceEnzyme ActivationGene SilencingHumansHuman Umbilical Vein Endothelial CellsMarine ToxinsModels, BiologicalMyosin-Light-Chain PhosphataseNitric OxideNitric Oxide Synthase Type IIIOxazolesPhosphorylationcalyculin ACatechinepigallocatechin gallateMarine ToxinsMyosin-Light-Chain PhosphataseNitric OxideNitric Oxide Synthase Type IIIOxazolesPhosphothreoninePPP1R12A protein, humanProtein Kinase CProtein Phosphatase 2RNA, Small InterferingTetradecanoylphorbol Acetate

Identifiers

PMID28300193
PMCPMC5353758
OpenAlexW2597018349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.