Trial reportScientific reports2017
Dynamic cortical participation during bilateral, cyclical ankle movements: effects of aging.
Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Factors influencing corticomuscular coherence for axial and lower limb musculature in a healthy population: a scoping review.Frontiers in human neuroscience · 2026Review
- Practical assessment of motor preparation-execution coupling during active ankle dorsiflexion in post-stroke gait: A pilot study.Clinical neurophysiology practice · 2026Article
- Acute changes in ankle dorsiflexor strength and fNIRS-Derived cortical activation following a single session of neuromuscular electrical stimulation in healthy older adults.Frontiers in aging · 2026Article
- Effects of Motor Preparation on Walking Ability in Active Ankle Dorsiflexion.Neurology international · 2025Article
- Electrophysiological Approaches to Understanding Brain-Muscle Interactions During Gait: A Systematic Review.Bioengineering (Basel, Switzerland) · 2025Review
- Exploration of the effects of Tai Chi practice on lower limb corticomuscular coherence during balance-demanding virtual reality conditions in older adults.Frontiers in aging neuroscience · 2025Article
- Null effects of musical groove on cortico-muscular coherence during isometric contraction.Neuroimage. Reports · 2022Article
- Age-specific modulation of intermuscular beta coherence during gait before and after experimentally induced fatigue.Scientific reports · 2020Article
- Corticospinal Control of Human Locomotion as a New Determinant of Age-Related Sarcopenia: An Exploratory Study.Journal of clinical medicine · 2020Article
- A pilot study assessing reliability and age-related differences in corticomuscular and intramuscular coherence in ankle dorsiflexors during walking.Physiological reports · 2020Article
- Corticomuscular Coherence and Its Applications: A Review.Frontiers in human neuroscience · 2019Review
- Dynamic cortical participation during bilateral, cyclical ankle movements: Effects of Parkinson's disease.PloS one · 2018Article
- Effect of training status on beta-range corticomuscular coherence in agonist vs. antagonist muscles during isometric knee contractions.Experimental brain research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise role of the human primary motor cortex in walking is unknown. Our previous study showed that the primary motor cortex may contribute to specific requirements of walking (i.e., maintaining a constant movement frequency and bilaterally coordinating the feet). Because aging can impair (i) the ability to fulfill the aforementioned requirements and (ii) corticomuscular communication, we hypothesized that aging would impair the motoneuronal recruitment by the primary motor cortex during bilateral cyclical movements. Here, we used corticomuscular coherence (i.e., coherence between the primary motor cortex and the active muscles) to examine whether corticomuscular communication is affected in older individuals during cyclical movements that shared some functional requirements with walking. Fifteen young men and 9 older men performed cyclical, anti-phasic dorsiflexion and plantarflexion of the feet while seated. Coherence between the midline primary motor cortex and contracting leg muscles cyclically increased in both age groups. However, the coherence of older participants was characterized by (i) lower magnitude and (ii) mediolaterally broader and more rostrally centered cortical distributions. These characteristics suggest that aging changes how the primary motor cortex participates in the cyclical movements, and such change may extend to walking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.