ArticleJournal of the American Society for Mass Spectrometry2017
Adduct Formation in ESI/MS by Mobile Phase Additives.
Article in Journal of the American Society for Mass Spectrometry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
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- A cost-efficient internal standard approach for busulfan quantification: MS-based investigation of adduct formation in therapeutic drug monitoring.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Article
- Receptor-Mitochondria Crosstalk in the Kynurenine Metabolic Pathway: Integrating Metabolomics and Clinical Mass Spectrometry.Antioxidants (Basel, Switzerland) · 2026Review
- Mass Spectrometry-Based Oral Meta-Omics Analysis-What We Know and What We Don't.Advances in experimental medicine and biology · 2026Review
- Antioxidant, Antibacterial, and Antidiabetic Activities ofTheScientificWorldJournal · 2026Article
- Adduct formation by coeluting endogenous biomolecules using ESI-MS : A comprehensive study on ESI efficiency.Analytical and bioanalytical chemistry · 2025Article
- Designing a set of reference standards for non-targeted analysis of polymer additives extracted from medical devices.Journal of exposure science & environmental epidemiology · 2025Article
- Efficient and Wide Chemical-Space Ionization of Organic Contaminants Using LC-MS with a Miniaturized Plasma Source Applying Different Discharge Gases.Analytical chemistry · 2025Article
- Longitudinal Fragment Profiles Based on Multi-Collision Energy Tandem Mass Spectra Improve the Accuracy of Metabolite Identification in Untargeted Metabolomics.Analytical chemistry · 2025Article
- A Novel UHPLC-MS/MS Based Method for Isomeric Separation and Quantitative Determination of Cyanogenic Glycosides in American Elderberry.Metabolites · 2024Article
- Article
- A Novel Bisquaternary Ammonium Compound as an Anion Sensor-ESI-MS and Fluorescence Study.International journal of molecular sciences · 2024Article
- Coated Blade Spray Ion Mobility Spectrometry.Analytical chemistry · 2024Article
- Synthesis, Structural Elucidation,ACS omega · 2024Article
- Uncovering the fragmentation and separation characteristics of sophorolipid biosurfactants with LC-MS-ESI.Journal of industrial microbiology & biotechnology · 2024Article
- Improving Quantitative Accuracy in Nontargeted Lipidomics by Evaluating Adduct Formation.Analytical chemistry · 2023Article
- A Critical Overview of HPLC-MS-Based Lipidomics in Determining Triacylglycerol and Phospholipid in Foods.Foods (Basel, Switzerland) · 2023Review
- Bypassing the Identification: MS2Quant for Concentration Estimations of Chemicals Detected with Nontarget LC-HRMS from MSAnalytical chemistry · 2023Article
- Exploring the Impact of Organic Solvent Quality and Unusual Adduct Formation during LC-MS-Based Lipidomic Profiling.Metabolites · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adduct formation is a common ionization method in electrospray ionization mass spectrometry (ESI/MS). However, this process is poorly understood and complicated to control. We demonstrate possibilities to control adduct formation via mobile phase additives in ESI positive mode for 17 oxygen and nitrogen bases. Mobile phase additives were found to be a very effective measure for manipulating the formation efficiencies of adducts. An appropriate choice of additive may increase sensitivity by up to three orders of magnitude. In general, sodium adduct [M + Na]
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Registered trials
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