Evidence map›Paper›PMID 28299426›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2017

Immunoexpression of GLUT-1 and angiogenic index in pleomorphic adenomas, adenoid cystic carcinomas, and mucoepidermoid carcinomas of the salivary glands.

Lélia Batista de Souza, Lucileide Castro de Oliveira, Cassiano Francisco Weege Nonaka, Maria Luiza Diniz de Sousa Lopes, Leão Pereira Pinto, Lélia Maria Guedes Queiroz

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Prognostic significance of GLUT-1 in adenoid cystic carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  8. Proliferation PET/CT Imaging of Salivary Gland Tumor.Diagnostics (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lélia Batista de SouzaPostgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil. leliabsouza@gmail.com.
Lucileide Castro de OliveiraPostgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Cassiano Francisco Weege NonakaState University of Paraíba, Campina Grande, PB, Brazil.
Maria Luiza Diniz de Sousa LopesPostgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Leão Pereira PintoPostgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Lélia Maria Guedes QueirozPostgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Estadual da Paraíba · BRUniversidade Federal do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate and compare the immunoexpression of glucose transporter-1 (GLUT-1) and angiogenic index between pleomorphic adenomas (PAs), adenoid cystic carcinomas (ACCs), and mucoepidermoid carcinomas (MECs) of the salivary glands, and establish associations with the respective subtype/histological grade. Twenty PAs, 20 ACCs, and 10 MECs were submitted to morphological and immunohistochemical analysis. GLUT-1 expression was semi-quantitatively evaluated and angiogenic index was assessed by microvessel counts using anti-CD34 antibody. Higher GLUT-1 immunoexpression was observed in the MECs compared to PAs and ACCs (p = 0.022). Mean number of microvessels was 66.5 in MECs, 40.4 in PAs, and 21.2 in ACCs (p < 0.001). GLUT-1 expression and angiogenic index showed no significant correlation in the tumors studied. Results suggest that differences in biological behavior of the studied tumors are related to GLUT-1. Benign and malignant salivary gland tumors differ in the angiogenic index; however, angiogenesis may be independent of the tumor cell's metabolic demand.

Indexed as

Neovascularization, PathologicAdenoma, PleomorphicBiomarkers, TumorCarcinoma, Adenoid CysticCarcinoma, MucoepidermoidExcitatory Amino Acid Transporter 2FemaleHumansImmunohistochemistryMaleMicrovesselsMiddle AgedNeoplasm GradingSalivary Gland NeoplasmsSalivary GlandsBiomarkers, TumorExcitatory Amino Acid Transporter 2Adenoid cystic carcinomaAngiogenic indexGlucose transporterMucoepidermoid carcinomaPleomorphic adenoma

Identifiers

PMID28299426
OpenAlexW2598539314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.