Evidence map›Paper›PMID 28299414›Full record

ArticleExperimental brain research2017

Photobiomodulation-induced changes in a monkey model of Parkinson's disease: changes in tyrosine hydroxylase cells and GDNF expression in the striatum.

Nabil El Massri, Ana P Lemgruber, Isobel J Rowe, Cécile Moro, Napoleon Torres, Florian Reinhart, Claude Chabrol, Alim-Louis Benabid, John Mitrofanis

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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  10. Photobiomodulation for Neurodegenerative Diseases: A Scoping Review.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Nabil El MassriDepartment of Anatomy F13, University of Sydney, Sydney, 2006, Australia.
Ana P LemgruberDepartment of Anatomy F13, University of Sydney, Sydney, 2006, Australia.
Isobel J RoweDepartment of Anatomy F13, University of Sydney, Sydney, 2006, Australia.
Cécile MoroUniversity of Grenoble Alpes, CEA, LETI, CLINATEC, MINATEC Campus, 38000, Grenoble, France.
Napoleon TorresUniversity of Grenoble Alpes, CEA, LETI, CLINATEC, MINATEC Campus, 38000, Grenoble, France.
Florian ReinhartUniversity of Grenoble Alpes, CEA, LETI, CLINATEC, MINATEC Campus, 38000, Grenoble, France.
Claude ChabrolUniversity of Grenoble Alpes, CEA, LETI, CLINATEC, MINATEC Campus, 38000, Grenoble, France.
Alim-Louis BenabidUniversity of Grenoble Alpes, CEA, LETI, CLINATEC, MINATEC Campus, 38000, Grenoble, France.
John MitrofanisDepartment of Anatomy F13, University of Sydney, Sydney, 2006, Australia. john.mitrofanis@sydney.edu.au.
The University of Sydney · AUUniversité Grenoble Alpes · FRClinatec · FRInstitut polytechnique de Grenoble · FRLaboratoire d'Électronique des Technologies de l'Information · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial application of red to infrared light, known also as photobiomodulation (PBM), has been shown to improve locomotor activity and to neuroprotect midbrain dopaminergic cells in rodent and monkey models of Parkinson's disease. In this study, we explored whether PBM has any influence on the number of tyrosine hydroxylase (TH)

Indexed as

AnimalsCaudate NucleusCell CountDisease Models, AnimalGlial Cell Line-Derived Neurotrophic FactorLow-Level Light TherapyMacaca fascicularisMiceMice, Inbred BALB CParkinsonian DisordersPutamenRatsRats, WistarTyrosine 3-MonooxygenaseGlial Cell Line-Derived Neurotrophic FactorTyrosine 3-Monooxygenase670 nm6OHDACaudateMPTPNear infrared lightPutamen

Identifiers

PMID28299414
OpenAlexW2604295597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.