ArticleCold Spring Harbor molecular case studies2017
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In one paragraph
Article in Cold Spring Harbor molecular case studies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Cardiomyopathy and mitochondrial encephalomyopathy in a female child associated with a heterozygous X-linked AIFM1 variant.Molecular and cellular pediatrics · 2026Article
- Perioperative Care of a Child With Combined Oxidative Phosphorylation Deficiency 6: Total Intravenous Anesthesia With Remimazolam.Journal of medical cases · 2025Article
- Apoptosis-inducing factor (AIF) at the crossroad of cell survival and cell death: implications for cancer and mitochondrial diseases.Cell communication and signaling : CCS · 2025Review
- Bioinformatics-led identification of pathophysiological hallmark genes in diabesotension via graph clustering method.Journal of diabetes and metabolic disorders · 2025Article
- AIF3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis.Nature communications · 2025Article
- Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction.Journal of translational medicine · 2024Article
- Expanding the spectrum of neonatal-onset AIFM1-associated disorders.Annals of clinical and translational neurology · 2023Article
- Apoptosis-inducing factor: a mitochondrial protein associated with metabolic diseases-a narrative review.Cardiovascular diagnosis and therapy · 2023Review
- Web-accessible application for identifying pathogenic transcripts with RNA-seq: Increased sensitivity in diagnosis of neurodevelopmental disorders.American journal of human genetics · 2023Article
- AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury.Biomedical journal · 2022Article
- Mitochondrial Epilepsy, a Challenge for Neurologists.International journal of molecular sciences · 2022Review
- The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence.Orphanet journal of rare diseases · 2022Review
- Case Report: A Novel Intronic Mutation inFrontiers in pediatrics · 2022Article
- Genetic mapping of renal glutathione suggests a novel regulatory locus on the murine X chromosome and overlap with hepatic glutathione regulation.Free radical biology & medicine · 2021Article
- Review
- Apoptosis-inducing factor plays a role in the pathogenesis of hepatic and renal injury during cholestasis.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Severe multisystem pathology, metabolic acidosis, mitochondrial dysfunction, and early death associated with an X-linkedCold Spring Harbor molecular case studies · 2021Article
- AIF3 splicing switch triggers neurodegeneration.Molecular neurodegeneration · 2021Article
- Skeletal Phenotypes Due to Abnormalities in Mitochondrial Protein Homeostasis and Import.International journal of molecular sciences · 2020Review
- Diatom-Derived Polyunsaturated Aldehydes Activate Similar Cell Death Genes in Two Different Systems: Sea Urchin Embryos and Human Cells.International journal of molecular sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Sarah U MortonDivision of Newborn Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Sanjay P PrabhuDepartment of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Hart G W LidovDepartment of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Jiahai ShiDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR.
Irina AnselmDepartment of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Catherine A BrownsteinDivision of Genetics and Genomics, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Matthew N BainbridgeRady Children's Institute for Genomic Medicine, San Diego, California 92123, USA.
Alan H BeggsDivision of Genetics and Genomics, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Sara O VargasDepartment of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Pankaj B AgrawalDivision of Newborn Medicine, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Boston Children's Hospital · USDana-Farber/Boston Children's Cancer and Blood Disorders Center · USHarvard University · USChildren’s Institute · USCity University of Hong Kong · HK
Funding
SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2MGenome Sequence-Based Screening for Childhood Risk and Newborn IllnessU19HD077671 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI BEGGS, ALAN H., GREEN, ROBERT C. · 2013 to 2018
$6.1MMouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2MSPEG is Critical in Skeletal Muscle Development and FunctionR01AR068429 · NIAMS · BOSTON CHILDREN'S HOSPITAL · PI AGRAWAL, PANKAJ B · 2015 to 2019
$1.9MNIAMS NIH HHS R01 AR068429NICHD NIH HHS P30 HD018655NICHD NIH HHS U19 HD077671NICHD NIH HHS U54 HD090255
Abstract
Apoptosis-inducing factor mitochondrion-associated 1 (AIFM1), encoded by the gene
Indexed as
Apoptosis Inducing FactorDNA, MitochondrialElectron TransportHumansInfantMitochondriaMitochondrial DiseasesMitochondrial EncephalomyopathiesMuscle, SkeletalMuscular DiseasesMutationAIFM1 protein, humanApoptosis Inducing FactorDNA, Mitochondrialbrain atrophycongenital lactic acidosiselevated brain lactate level by MRSinfantile encephalopathylethal infantile mitochondrial myopathymitochondrial encephalopathy
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.