ArticleBioMed research international2017
An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft.
Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- Antibiotic-Loaded Calcium Sulphate Beads in Wound Management: A Scoping Review of Emerging Applications in Plastic and Reconstructive Surgery.International wound journal · 2026Article
- Conventional Versus Regenerative Methods for Wound Healing: A Comparative Experimental Study on a Sheep Model.Medicina (Kaunas, Lithuania) · 2024Article
- Meek Micro-Skin Grafting and Acellular Dermal Matrix in Pediatric Patients: A Novel Approach to Massive Extravasation Injury.Journal of clinical medicine · 2023Article
- A comparative study of full-thickness skin grafting with and without subcutaneous fat preservation.International wound journal · 2023Article
- Roles of negative pressure wound therapy for scar revision.Frontiers in physiology · 2023Review
- One-Stage Coverage of Leg Region Defects with STSG Combined with VAC Dressing Improves Early Patient Mobilisation and Graft Take: A Comparative Study.Journal of clinical medicine · 2022Article
- Clinical Evaluation of the Efficacy and Tolerability of RigenaseJournal of clinical medicine · 2022Article
- Effectiveness of negative pressure wound therapy: Minimum five-year follow-up and review of the literature.Joint diseases and related surgery · 2022Review
- Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.International wound journal · 2018Review
- Micelle-Coated, Hierarchically Structured Nanofibers with Dual-Release Capability for Accelerated Wound Healing and Infection Control.Advanced healthcare materials · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive skin defect represents a real problem and major challenge in plastic and reconstructive surgery. On one hand, skin grafts offer a practical method to deal with skin defects despite their unsuitability for several complicated wounds. On the other hand, negative pressure wound therapy (NPWT), applied before skin grafting, promotes granulation tissue growth. The aim of the study is to evaluate the improvement in wound healing given by the merger of these two different approaches. We treated 23 patients for large wounds of multiple factors. Of these, 15 were treated with the application of V.A.C.® Therapy (KCI Medical S.r.l., Milan, Italy), in combination with skin grafts after a prior unsuccessful treatment of 4 weeks with mesh skin grafts and dressings. Another 8 were treated with only mesh skin graft. Pain reduction and wound area reduction were found statistically significant (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.