ArticleAdvanced biomedical research2017
Expression of Estrogen Receptor Alpha in Malignant Melanoma.
Article in Advanced biomedical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
- Centromere Protein F Is a Potential Prognostic Biomarker and Target for Cutaneous Melanoma.Biomedicines · 2025Article
- Efficient Consecutive Synthesis of Fluorinated Isoflavone Analogs, X-Ray Structures, Hirshfeld Analysis, and Anticancer Activity Assessment.Molecules (Basel, Switzerland) · 2025Article
- A Narrative Review of the Role of Estrogen (Receptors) in Melanoma.International journal of molecular sciences · 2024Review
- The emerging role and clinicopathological significance of MFSD12 in cancer and lysosomal storage diseases.Frontiers in pharmacology · 2024Review
- Different Susceptibilities of Human Melanoma Cell Lines to G2/M Blockage and Cell Death Activation in Response to the Estrogen Receptor β agonist LY500307.Journal of Cancer · 2022Article
- Role of estrogen receptors in health and disease.Frontiers in endocrinology · 2022Review
- Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma.The Journal of clinical investigation · 2021Article
- Molecular Proof of a Clinical Concept: Expression of Estrogen Alpha-, Beta-Receptors and G Protein-Coupled Estrogen Receptor 1 (GPER) in Histologically Assessed Common Nevi, Dysplastic Nevi and Melanomas.Medicina (Kaunas, Lithuania) · 2021Article
- Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer.Archives of toxicology · 2021Article
- Identification of Signatures of Prognosis Prediction for Melanoma Using a Hypoxia Score.Frontiers in genetics · 2020Article
- Prognostic genes of melanoma identified by weighted gene co-expression network analysis and drug repositioning using a network-based method.Oncology letters · 2019Article
- Article
- Interference from LncRNA SPRY4-IT1 restrains the proliferation, migration, and invasion of melanoma cells through inactivating MAPK pathway by up-regulating miR-22-3p.International journal of clinical and experimental pathology · 2019Article
- Upregulation of UHRF1 promotes the progression of melanoma by inducing cell proliferation.Oncology reports · 2018Article
- A cancer registry-based analysis on the non-white populations reveals a critical role of the female sex in early-onset melanoma.Cancer causes & control : CCC · 2018Article
- Determine the Role of FSH Receptor Binding Inhibitor in Regulating Ovarian Follicles Development and Expression of FSHR and ERBioMed research international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFeatures of malignant melanoma (MM) vary in the different geographic regions of the world. This may be attributable to environmental, ethnic, and genetic factors. The aim of this study was to determine the expression of estrogen receptor alpha (ER-α) in MM in Isfahan, Iran. MATERIALS AND
methodsThis study was planned as a descriptive, analytical, cross-sectional investigation. During this study, paraffin-embedded tissue blocks of patients with a histopathologic diagnosis of MM was studied for ER-α using immunohistochemistry (IHC).
resultsIn this study, 38 patients (female/male; 20/18) with a definite diagnosis of malignant cutaneous melanoma and mean age of 52.4 ± 11.2 years were investigated. Using envision IHC staining, there were not any cases with ER-α expression.
conclusionIn confirmation to the most previous studies, expression of ER-α was negative in MM. It is recommended to investigate the expression of estrogen receptor beta and other markers in MM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.