Evidence map›Paper›PMID 28299192›Full record

ReviewF1000Research2017

Respiratory rhythm generation: triple oscillator hypothesis.

Tatiana M Anderson, Jan-Marino Ramirez

Abstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. HomozygousNeurology. Genetics · 2025
    Article
  6. Endogenous opioids and the development of the mammalian respiratory control network.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Sensing, feeling and regulating: investigating the association of focal brain damage with voluntary respiratory and motor control.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Motor Dysfunctions in Fibromyalgia Patients: The Importance of Breathing.Open access rheumatology : research and reviews · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Optogenetic stimulation of pre-Bötzinger complex reveals novel circuit interactions in swallowing-breathing coordination.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Inspiratory rhythm generation is stabilized byJournal of neurophysiology · 2022
    Article
  20. Central respiratory chemoreception.Handbook of clinical neurology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tatiana M AndersonCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Graduate Program for Neuroscience, University of Washington School of Medicine, Seattle, WA, USA.
Jan-Marino RamirezCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Neurological Surgery and Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0002-5626-3999

Funding

Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4M
Unraveling respiratory rhythm generation in the medullary networkR01HL126523 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI Jan M. Ramirez · 2015 to 2026
$8.3M
NHLBI NIH HHS P01 HL090554NHLBI NIH HHS R01 HL126523
6 · The paper itself

Abstract

Breathing is vital for survival but also interesting from the perspective of rhythm generation. This rhythmic behavior is generated within the brainstem and is thought to emerge through the interaction between independent oscillatory neuronal networks. In mammals, breathing is composed of three phases - inspiration, post-inspiration, and active expiration - and this article discusses the concept that each phase is generated by anatomically distinct rhythm-generating networks: the preBötzinger complex (preBötC), the post-inspiratory complex (PiCo), and the lateral parafacial nucleus (pF

Indexed as

breathingnetworksOscillatorspacemakerPostinspirationpreBotzinger complexRespirationrhythm generation

Identifiers

PMID28299192
PMCPMC5310385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.