ReviewF1000Research2017
Recent advances in understanding and managing IgG4-related disease.
Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- European Guideline on IgG4-related digestive disease - UEG and SGF evidence-based recommendations.United European gastroenterology journal · 2020Guideline
- Therapeutic Uses of Rituximab and Clinical Features in Immunoglobulin G4-Related Disease: A Systematic Review.Cureus · 2023Review
- Article
- Multimodality Imaging Evaluation of Coronary IgG4-Related Disease: A "Tumor-Like" Cardiac Lesion.Diagnostics (Basel, Switzerland) · 2022Article
- Long-term outcomes of ocular adnexal lesions in IgG4-related ophthalmic disease.The British journal of ophthalmology · 2020Article
- Immunoglobulin G4-related disease mimicking gallbladder cancer with associated choledochal cyst: A case report of a malignant masquerade.JGH open : an open access journal of gastroenterology and hepatology · 2019Article
- A case of eosinophilic granulomatosis with polyangiitis complicated with a similar condition to IgG4 related lung disease.BMC pulmonary medicine · 2019Article
- IgG4 drives M2a macrophages to a regulatory M2b-like phenotype: potential implication in immune tolerance.Allergy · 2019Article
- Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: clinical manifestations and treatment efficacy.Arthritis research & therapy · 2019Article
- Retrospective single-centre analysis of IgG4-related disease patient population and treatment outcomes between 2007 and 2017.Rheumatology advances in practice · 2019Article
- A medical mirroring: chronic myelomonocytic leukemia mimicking immunoglobulin G4-related disease.American journal of translational research · 2019Article
- Immunoglobulin G4-related sclerosing cholangitis.The Korean journal of internal medicine · 2018Review
- IgG4-Related Aortitis.European journal of case reports in internal medicine · 2018Article
- Humoral immune response in adult Brazilian patients with Mucolipidosis III gamma.Genetics and molecular biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4-related disease was only recently discovered, so its description, management, and new discoveries related to its etiology are rapidly evolving. Because IgG4 itself is a unique antibody which is intimately related to the diagnosis of the disease, the role of plasmablasts in the pathophysiology remains an active area of discussion. Recent studies have uncovered a possible role for CD4-positive cytotoxic T lymphocytes, T follicular helper cells, and M2 macrophages. The clinical presentation is variable and can be vague, as this disease affects many organs and new presentations are continuing to be described. The diagnosis depends on clinical and histopathological assessment. The mainstay of treatment is with glucocorticoids, but rituximab has recently shown promise. Monitoring disease activity using imaging modalities (including positron emission tomography) and serum markers is imperative, as relapses are common. IgG4-related disease spans many medical disciplines but is a treatable condition with which all clinicians should be familiar.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.