Evidence map›Paper›PMID 28299006›Full record

ArticleJournal of ophthalmic & vision research

Characteristics of Macular Edema in Behcet Disease after Intravitreal Bevacizumab Injection.

Fariba Ghassemi, Sohrab Afshari Mirak, Hormoz Chams, Siamak Sabour, Mehdi Nilli Ahmadabadi, Fereidoun Davatchi, Farhad Shahram

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fariba GhassemiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; The Retina and vitreous surgery service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sohrab Afshari MirakEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Hormoz ChamsEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; The Retina and vitreous surgery service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Siamak SabourSafety Promotion and Injury Prevention Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Clinical Epidemiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi Nilli AhmadabadiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; The Retina and vitreous surgery service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Fereidoun DavatchiRheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Farhad ShahramRheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Farabi Hospital · IRTehran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRShariati Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effect of intravitreal bevacizumab (IVB) injection on macular edema (ME) secondary to Behcet's disease.

methodsThis prospective case series included 15 patients with bilateral ME due to Behcet's disease. Intravitreal bevacizumab was injected into the more severely involved eye; the contralateral eye was evaluated as the control. Patients were followed up with comprehensive ocular examination, optical coherence tomography, and fluorescein angiography (FA) for a minimum of 6 months by a single ophthalmologist.

resultsPatients with a mean age of 30.6 ± 7.4 years received a mean number of 3.3 IVB injections during the 6 months. The mean preinjection vision was 0.6 ± 0.3 and 0.4 ± 0.4 LogMAR in the case and control groups, respectively, with no significant improvement at 6 months. Mean central foveal thickness was 375.3 ± 132.1 and 307.2 ± 84.5 μm in the case and control groups, respectively, and these changed to 401 ± 199.9 (

conclusionDuring a 6-month period, IVB injections based on an as-needed protocol provided no statistically significant improvement in VA and ME.

Indexed as

Behcet's DiseaseIntravitreal BevacizumabMacular EdemaUveitis

Identifiers

PMID28299006
PMCPMC5340063
OpenAlexW2588047162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.