ReviewJournal of ultrasound2017
Image-guided thermal ablation of benign thyroid nodules.
Review in Journal of ultrasound, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 5 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Complications of minimally invasive treatments of benign thyroid nodules: preventive andmanaging strategies: A systematic review.La Radiologia medica · 2026Pooled it
- Meta-Analysis of the Application Effect of Different Modalities of Thermal Ablation and Surgical Treatment in Papillary Thyroid Microcarcinoma.Disease markers · 2022Pooled it
- Pooled it
- Pooled it
- Pooled it
- Elastofibroma dorsi: imaging-guided minimally invasive treatment using percutaneous COSkeletal radiology · 2026Article
- Thermal Ablation as a Non-Surgical Alternative for Thyroid Nodules: A Review of Current Evidence.Medicina (Kaunas, Lithuania) · 2025Review
- Microwave ablation of ectopic mediastinal parathyroid: A case report.Radiology case reports · 2025Article
- Comparison of efficacy and safety of different minimally invasive therapies for thyroid nodules: A network meta-analysis.Endocrine · 2024Review
- Current role of interventional radiology in thyroid nodules.Frontiers in endocrinology · 2024Review
- Modern Surgical Techniques of Thyroidectomy and Advances in the Prevention and Treatment of Perioperative Complications.Cancers · 2023Review
- Multiple overlapping microwave ablation in benign thyroid nodule: a single-center 24-month study.European thyroid journal · 2023Article
- Total thyroidectomy versus hemithyroidectomy with intraoperative radiofrequency ablation for unilateral thyroid cancer with contralateral nodules: A propensity score matching study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2022Article
- Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up.BMC medical imaging · 2022Article
- Article
- A New Perspective for Predicting the Therapeutic Success of RFA in Solid BTNs: Quantitative Initial RFA Ratio by Contrast-Enhanced Ultrasound.Frontiers in endocrinology · 2022Article
- Safety and Efficacy of Radiofrequency Ablation of Thyroid Nodules-Expanding Treatment Options in the United States.Journal of the Endocrine Society · 2021Article
- Combining high-intensity focused ultrasound (HIFU) ablation with percutaneous ethanol injection (PEI) in the treatment of benign thyroid nodules.European radiology · 2021Article
- A Computational Study on Temperature Variations in MRgFUS Treatments Using PRF Thermometry Techniques and Optical Probes.Journal of imaging · 2021Article
- Ultrasound-guided microwave ablation of benign thyroid nodules: effects on inflammatory factors and thyroid function.American journal of translational research · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benign thyroid nodules are a common disease in the general population. Most often, they are completely asymptomatic and discovered occasionally during routine ultrasound examinations, and do not require any treatment. When thyroid nodules become symptomatic, surgical excision is still considered standard treatment. In the last few years, several experiences in the treatment of benign thyroid nodules through image-guided percutaneous thermal ablation have been reported with encouraging results, so that currently, these treatments are often proposed as first-choice options for patients with symptomatic benign thyroid nodules. In this paper, we discuss the present literature on the topic, focusing on different techniques available for image-guided percutaneous ablation, particularly radiofrequency (RFA), laser (LA), microwave (MWA), and high-intensity-focus ultrasound (HIFU). Little evidence about the efficacy of MWA and HIFU is now available. According to the literature, good results have been obtained with RFA and LA. Regarding RFA, volume reduction after ablative treatment has been found to range from 47 to 84 % at 3-6 months, and from 62 to 93 % at 1 year; LA also seems to be effective in achieving shrinkage of thyroid nodules, with volume reduction from 37 to 81 % at 3-6 months, and from 13 to 82 % at 1-year follow-up. Moreover, applications of advanced image-guidance modality, such as contrast-enhanced ultrasound and virtual navigation with fusion imaging, are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.