Evidence map›Paper›PMID 28298884›Full record

ArticleFrontiers in neuroscience2017

Physical Exercise Restores the Generation of Newborn Neurons in an Animal Model of Chronic Epilepsy.

Fabricio N Mendonça, Luiz E C Santos, Antônio M Rodrigues, Sérgio Gomes da Silva, Ricardo M Arida, Gilcélio A da Silveira, Fulvio A Scorza, Antônio-Carlos G Almeida

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In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabricio N MendonçaLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei São João del-Rei, Brazil.
Luiz E C SantosLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei São João del-Rei, Brazil.
Antônio M RodriguesLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei São João del-Rei, Brazil.
Sérgio Gomes da SilvaInstituto do Cérebro, Hospital Israelita Albert EinsteinSão Paulo, Brazil; Núcleo de Pesquisas Tecnológicas, Universidade de Mogi das CruzesMogi das Cruzes, Brazil.
Ricardo M AridaDepartamento de Fisiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP) São Paulo, Brazil.
Gilcélio A da SilveiraLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei São João del-Rei, Brazil.
Fulvio A ScorzaLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-ReiSão João del-Rei, Brazil; Disciplina de Neurologia Experimental, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP)São Paulo, Brazil.
Antônio-Carlos G AlmeidaLaboratório de Neurociência Experimental e Computacional, Departamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei São João del-Rei, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurogenesis impairment is associated with the chronic phase of the epilepsy in humans and also observed in animal models. Recent studies with animal models have shown that physical exercise is capable of improving neurogenesis in adult subjects, alleviating cognitive impairment and depression. Here, we show that there is a reduction in the generation of newborn granule cells in the dentate gyrus of adult rats subjected to a chronic model of epilepsy during the

Indexed as

DCXectopic newborn neuronsepilepsyneurogenesisphysical exercise

Identifiers

PMID28298884
PMCPMC5331057

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.