Evidence map›Paper›PMID 28298808›Full record

ArticleDisease markers2017

Diagnostic Value of Autoantibodies against Ezrin in Esophageal Squamous Cell Carcinoma.

Lan Li, Ming Liu, Jian-Bang Lin, Xin-Bin Hong, Wen-Xia Chen, Hong Guo, Li-Yan Xu, Yi-Wei Xu, En-Min Li, Yu-Hui Peng

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Detecting the location and significance of Ezrin protein expression in hepatocellular carcinoma.International journal of clinical and experimental pathology · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lan LiShantou University Medical College, Shantou 515041, China.
Ming LiuShantou University Medical College, Shantou 515041, China.
Jian-Bang LinDepartment of Radiology, Cancer Hospital, Shantou University Medical College, Shantou 515041, China.
Xin-Bin HongShantou University Medical College, Shantou 515041, China.
Wen-Xia ChenShantou University Medical College, Shantou 515041, China.
Hong GuoDepartment of Radiation Oncology, Cancer Hospital, Shantou University Medical College, Shantou 515041, China.
Li-Yan XuInstitute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, China.
Yi-Wei XuDepartment of Clinical Laboratory Medicine, Cancer Hospital, Shantou University Medical College, Shantou 515041, China; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Guangdong Higher Education Institutes, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0002-8670-592X
En-Min LiThe Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Guangdong Higher Education Institutes, Shantou University Medical College, Shantou 515041, China; Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0001-6375-3614
Yu-Hui PengDepartment of Clinical Laboratory Medicine, Cancer Hospital, Shantou University Medical College, Shantou 515041, China; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Guangdong Higher Education Institutes, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0002-1866-4679
Shantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC), one of the most common malignancies worldwide, is a highly aggressive and homogeneous entity occurring in esophageal squamous epithelium, and a reliable noninvasive test for early detection is needed. A recent study showed that serum autoantibodies against Ezrin could be detected in patients with pancreatic cancer. Here, we assessed whether autoantibodies against Ezrin could have diagnostic relevance for early ESCC. We analyzed autoantibodies against Ezrin in sera of 98 normal controls and 149 patients with ESCC. Ezrin autoantibodies levels were evaluated by enzyme-linked immunosorbent assay (ELISA). Results showed that higher levels of autoantibodies against Ezrin were observed in serum samples from patients with ESCC than in serum from normal controls (

Indexed as

AgedAutoantibodiesBiomarkers, TumorCarcinoma, Squamous CellCase-Control StudiesCytoskeletal ProteinsEnzyme-Linked Immunosorbent AssayEsophageal NeoplasmsEzrinFemaleHumansMaleMiddle AgedAutoantibodiesBiomarkers, TumorCytoskeletal ProteinsEzrin

Identifiers

PMID28298808
PMCPMC5337388
OpenAlexW2588596417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.