Evidence map›Paper›PMID 28298597›Full record

ArticleJournal of virology2017

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability.

Katherine A Scott, Abhay Kotecha, Julian Seago, Jingshan Ren, Elizabeth E Fry, David I Stuart, Bryan Charleston, Francois F Maree

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Katherine A ScottTransboundary Animal Disease Programme, ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa.
Abhay KotechaDivision of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.
Julian SeagoThe Pirbright Institute, Pirbright, Woking, United Kingdom.
Jingshan RenDivision of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.
Elizabeth E FryDivision of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.
David I StuartDivision of Structural Biology, University of Oxford, Headington, Oxford, United Kingdom.
Bryan CharlestonThe Pirbright Institute, Pirbright, Woking, United Kingdom.
Francois F MareeTransboundary Animal Disease Programme, ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa mareef@arc.agric.za.
University of Oxford · GBThe Pirbright Institute · GBUniversity of Pretoria · ZADiamond Light Source · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Medical Research Council G100099Medical Research Council G1100525Medical Research Council MR/N00065X/1Wellcome Trust 089755Wellcome Trust 090532/Z/09/Z
6 · The paper itself

Abstract

Foot-and-mouth disease virus (FMDV), particularly strains of the O and SAT serotypes, is notoriously unstable. Consequently, vaccines derived from heat-labile SAT viruses have been linked to the induction of immunity with a poor duration and hence require more frequent vaccinations to ensure protection.

Indexed as

Amino Acid SubstitutionAnimalsFoot-and-Mouth Disease VirusGenomic InstabilityHydrogen-Ion ConcentrationImmunogenicity, VaccineIonsKineticsMutationSerogroupSodium ChlorideTemperatureVaccine PotencyViral VaccinesIonsSodium ChlorideViral VaccinesFMDVSAT2stability

Identifiers

PMID28298597
PMCPMC5411616
OpenAlexW2602359998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.