Evidence map›Paper›PMID 28298430›Full record

ArticleGenome research2017

metaSPAdes: a new versatile metagenomic assembler.

Sergey Nurk, Dmitry Meleshko, Anton Korobeynikov, Pavel A Pevzner

Registry-linked trialAbstract read
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07169123 (Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD), which is not on this map. Cited by 2,561 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,561citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07169123 recruitingnot on this mapstarted 2025, after this paper: background citation

Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD

TypeobservationalSponsorMcMaster UniversityRan2025 to 2029Enrolled300ConditionsCrohns Disease
3 · Its place in the literature

Who cites it

2,561 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Metagenome-assembled genomes fromMicrobiology resource announcements · 2026
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2,501 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sergey NurkCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia 199004.
Dmitry MeleshkoCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia 199004.
Anton KorobeynikovCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia 199004.ORCID 0000-0002-2937-9259
Pavel A PevznerCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia 199004.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While metagenomics has emerged as a technology of choice for analyzing bacterial populations, the assembly of metagenomic data remains challenging, thus stifling biological discoveries. Moreover, recent studies revealed that complex bacterial populations may be composed from dozens of related strains, thus further amplifying the challenge of metagenomic assembly. metaSPAdes addresses various challenges of metagenomic assembly by capitalizing on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes. We benchmark metaSPAdes against other state-of-the-art metagenome assemblers and demonstrate that it results in high-quality assemblies across diverse data sets.

Indexed as

MetagenomeSoftwareContig MappingGenome, BacterialGenomicsSequence Analysis, DNA

Identifiers

PMID28298430
PMCPMC5411777

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.