Evidence map›Paper›PMID 28298304›Full record

ArticleJournal of neurophysiology2017

No consistent effect of cerebellar transcranial direct current stimulation on visuomotor adaptation.

Roya Jalali, R Chris Miall, Joseph M Galea

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Neurophysiology of cerebellar ataxias and gait disorders.Clinical neurophysiology practice · 2023
    Review
  18. Article
  19. Article
  20. A Brief History of Cerebellar Neurostimulation.Cerebellum (London, England) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roya JalaliPhysical Sciences of Imaging in the Biomedical Sciences, Doctoral Training Centre, University of Birmingham, Birmingham, United Kingdom; and rxj237@bham.ac.uk Royadjalali@gmail.com.
R Chris MiallSchool of Psychology, University of Birmingham, Birmingham, United Kingdom.
Joseph M GaleaSchool of Psychology, University of Birmingham, Birmingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebellar transcranial direct current stimulation (ctDCS) is known to enhance adaptation to a novel visual rotation (visuomotor adaptation), and it is suggested to hold promise as a therapeutic intervention. However, it is unknown whether this effect is robust across varying task parameters. This question is crucial if ctDCS is to be used clinically, because it must have a consistent and robust effect across a relatively wide range of behaviors. The aim of this study was to examine the effect of ctDCS on visuomotor adaptation across a wide range of task parameters that were systematically varied. Therefore, 192 young healthy individuals participated in 1 of 7 visuomotor adaptation experiments in either an anodal or sham ctDCS group. Each experiment examined whether ctDCS had a positive effect on adaptation when a unique feature of the task was altered: position of the monitor, offline tDCS, use of a tool, and perturbation schedule. Although we initially replicated the previously reported positive effect of ctDCS on visuomotor adaptation, this was not maintained during a second replication study or across a large range of varying task parameters. At the very least, this may call into question the validity of using ctDCS within a clinical context where a robust and consistent effect across behavior would be required.

Indexed as

Transcranial Direct Current StimulationAdaptation, PhysiologicalAdaptation, PsychologicalAdultCerebellumFemaleHandHumansMaleMotor ActivityNeuropsychological TestsReproducibility of ResultsVisual Perceptionadaptationbrain stimulationcerebellummotor learningtDCS

Identifiers

PMID28298304
PMCPMC5539446

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.