Evidence map›Paper›PMID 28298303›Full record

ArticleJournal of neurophysiology2017

AMPA receptor-mediated rapid EPSCs in vestibular calyx afferents.

Matthew E Kirk, Frances L Meredith, Timothy A Benke, Katherine J Rennie

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Expression of hyperpolarization-activated current (Journal of neurophysiology · 2023
    Article
  6. Article
  7. Article
  8. Current Response in CaFrontiers in neuroscience · 2021
    Article
  9. Article
  10. KNeuroscience · 2020
    Article
  11. Article
  12. Sensory Hair Cells: An Introduction to Structure and Physiology.Integrative and comparative biology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew E KirkDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Frances L MeredithDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Timothy A BenkeDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.
Katherine J RennieDepartment of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado; katie.rennie@ucdenver.edu.
University of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the vestibular periphery neurotransmission between hair cells and primary afferent nerves occurs via specialized ribbon synapses. Type I vestibular hair cells (HCIs) make synaptic contacts with calyx terminals, which enclose most of the HCI basolateral surface. To probe synaptic transmission, whole cell patch-clamp recordings were made from calyx afferent terminals isolated together with their mature HCIs from gerbil crista. Neurotransmitter release was measured as excitatory postsynaptic currents (EPSCs) in voltage clamp. Spontaneous EPSCs were classified as simple or complex. Simple events exhibited a rapid rise time and a fast monoexponential decay (time constant < 1 ms). The remaining events, constituting ~40% of EPSCs, showed more complex characteristics. Extracellular Sr

Indexed as

Excitatory Postsynaptic Potentials3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterAnimalsBenzothiadiazinesCalcium Channel BlockersCalcium Channels, L-TypeCells, CulturedDipeptidesFemaleGerbillinaeHair Cells, VestibularMaleNifedipineQuinoxalinesReceptors, AMPAStrontium2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterBenzothiadiazinesCalcium Channel BlockersCalcium Channels, L-TypecyclothiazideDipeptidesgamma-glutamylglycineNifedipineQuinoxalinesReceptors, AMPAStrontiumAMPA receptorcristacyclothiazideglutamatetype I hair cell

Identifiers

PMID28298303
PMCPMC5491709
OpenAlexW2600278838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.