Evidence map›Paper›PMID 28297716›Full record

ArticleNature2017

RNA m

Yang Xiang, Benoit Laurent, Chih-Hung Hsu, Sigrid Nachtergaele, Zhike Lu, Wanqiang Sheng, Chuanyun Xu, Hao Chen, Jian Ouyang, Siqing Wang and 6 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 555 papers.

0numbers the graph read from it
0cells of the map it votes in
555citing papers in PubMed
33.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

555 citing papers in PubMed, 952 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. WTAP tetramer ensures mEMBO reports · 2026
    Article
  9. Review
  10. Article
  11. Methylation marks breast cancer metastasis: The roles of mThe Journal of biological chemistry · 2026
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. mCell death and differentiation · 2026
    Article
  18. Article
  19. Article
  20. Review

495 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Yang XiangDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Benoit LaurentDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Chih-Hung HsuDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Sigrid NachtergaeleDepartment of Chemistry, University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Zhike LuDepartment of Chemistry, University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Wanqiang ShengDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Chuanyun XuDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Hao ChenDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Jian OuyangMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts 02109, USA.
Siqing WangDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Dominic LingDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Pang-Hung HsuDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung City 202, Taiwan.
Lee ZouMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts 02109, USA.
Ashwini JambhekarDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Chuan HeDepartment of Chemistry, University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Yang ShiDivision of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Boston Children's Hospital · USUniversity of Chicago · USHarvard University · USMassachusetts General Hospital · USNational Taiwan Ocean University · TW

Funding

Training Program in Newborn and Developmental DiseasesT32HD007466 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI KOUREMBANAS, STELLA · 1994 to 2016
$8.0M
Histone Demethylases and Regulation of Chromatin and Transcription in EukaryotesR01CA118487 · NCI · HARVARD MEDICAL SCHOOL · PI SHI, YANG · 2006 to 2017
$3.6M
National Institutes of Health 4 T32 HD 7466-20NCI NIH HHS R01 CA118487NICHD NIH HHS T32 HD007466
6 · The paper itself

Abstract

Cell proliferation and survival require the faithful maintenance and propagation of genetic information, which are threatened by the ubiquitous sources of DNA damage present intracellularly and in the external environment. A system of DNA repair, called the DNA damage response, detects and repairs damaged DNA and prevents cell division until the repair is complete. Here we report that methylation at the 6 position of adenosine (m

Indexed as

MethylationUltraviolet RaysAlpha-Ketoglutarate-Dependent Dioxygenase FTOAnimalsBiocatalysisCell LineCell SurvivalDNA DamageDNA-Directed DNA PolymeraseDNA RepairDNA ReplicationHumansMethyltransferasesMicePoly ARNAAlpha-Ketoglutarate-Dependent Dioxygenase FTODNA-Directed DNA PolymeraseFTO protein, humanMethyltransferasesMETTL3 protein, humanPOLK protein, humanPoly ARNAY-Family DNA Polymerases

Identifiers

PMID28297716
PMCPMC5490984
OpenAlexW2597375791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.