ArticleOphthalmic surgery, lasers & imaging retina2017
Ultra-Wide-Field Fundus Autofluorescence and Spectral-Domain Optical Coherence Tomography Findings in Syphilitic Outer Retinitis.
Article in Ophthalmic surgery, lasers & imaging retina, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Putative mechanisms of ocular inflammation in syphilis.Journal of ophthalmic inflammation and infection · 2026Review
- Reliability of quantitative and qualitative chorioretinal uveitis lesion analysis on blue, green, and near-infrared fundus autofluorescence and color fundus photography.Scientific reports · 2026Article
- Clinical features in four patients with syphilitic outer retinopathy.Japanese journal of ophthalmology · 2025Article
- Persistent syphilitic ocular manifestations despite treatment: a case series.Journal of ophthalmic inflammation and infection · 2024Article
- Fundus Autofluorescence in Posterior and Panuveitis-An Under-Estimated Imaging Technique: A Review and Case Series.Biomolecules · 2024Review
- Challenges in posterior uveitis-tips and tricks for the retina specialist.Journal of ophthalmic inflammation and infection · 2023Review
- Presentation of Ocular Syphilis with Bilateral Optic Neuropathy.Neuro-ophthalmology (Aeolus Press) · 2023Article
- Retinal dysfunction of syphilitic outer retinopathy.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Masqueraders of multiple evanescent white dot syndrome (MEWDS).International ophthalmology · 2020Article
- Advances in Retinal Optical Imaging.Photonics · 2018Article
- Syphilitic Outer Retinopathy: A Case Report and Review of the Literature.Journal of vitreoretinal diseasesReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectiveTo determine the ultra-wide-field fundus autofluorescence (UWFFAF) and optical coherence tomography (OCT) features of syphilitic outer retinopathy (SOR). PATIENTS AND
methodsRetrospective chart review.
resultsThree patients with SOR were investigated. Treatment with parenteral penicillin led to improvement of outer retinopathy, visual acuity, and symptoms. UWFFAF showed speckled hyperautofluorescence, hypoautofluorescence, and normal autofluorescence, similar to what has been described as a trizonal pattern in acute zonal occult outer retinopathy (AZOOR) in the chronic case of SOR, but with hyperautofluorescent areas in the two acute cases. OCT showed disruption of the photoreceptor outer segment ellipsoid zone and external limiting membrane, which improved after penicillin treatment, and corresponded to normalization of the hyperautofluorescent areas on UWFFAF. There was irregularity and nodular thickening of retinal pigment epithelium on OCT in areas of mottled hyperautofluorescence.
conclusionSOR can present similarly to AZOOR on UWFFAF and should be highly suspected in cases presenting like AZOOR. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:208-215. ].
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