Evidence map›Paper›PMID 28296347›Full record

ArticleJournal of tissue engineering and regenerative medicine2018

GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats.

Bingkun K Chen, Nicolas N Madigan, Jeffrey S Hakim, Mahrokh Dadsetan, Siobhan S McMahon, Michael J Yaszemski, Anthony J Windebank

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Open-Spaced Ridged Hydrogel Scaffolds Containing TiOInternational journal of molecular sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Melatonin signalling in Schwann cells during neuroregeneration.Frontiers in cell and developmental biology · 2022
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Bingkun K ChenDepartment of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota.
Nicolas N MadiganDepartment of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota.
Jeffrey S HakimDepartment of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota.
Mahrokh DadsetanDepartment of Orthopedic Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota.
Siobhan S McMahonDepartment of Medicine, Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway.
Michael J YaszemskiDepartment of Orthopedic Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota.
Anthony J WindebankDepartment of Neurology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-3481-0274
Mayo Clinic · USOllscoil na Gaillimhe – University of Galway · IE

Funding

Biodegradable Polymer Implants for Spinal Cord RepairR01EB002390 · NIBIB · MAYO CLINIC ROCHESTER · PI WINDEBANK, ANTHONY JOHN · 2003 to 2006
$1.3M
NIBIB NIH HHS R01 EB002390
6 · The paper itself

Abstract

Positively-charged oligo[poly(ethylene glycol)fumarate] (OPF

Indexed as

AnimalsAxonsFumaratesGlial Cell Line-Derived Neurotrophic FactorHumansHydrogelsNerve RegenerationPolyethylene GlycolsRats, Sprague-DawleyRecovery of FunctionRemyelinationSchwann CellsSpinal Cord InjuriesTissue ScaffoldsFumaratesGlial Cell Line-Derived Neurotrophic FactorHydrogelspoly(ethylene glycol fumarate)Polyethylene Glycolsglial-derived neurotrophic factorhydrogeloligo[poly(ethylene glycol)fumarate]scaffoldsSchwann cellsspinal cord injury

Identifiers

PMID28296347
PMCPMC13170761
OpenAlexW2594571070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.