Evidence map›Paper›PMID 28296226›Full record

Trial reportJournal of diabetes investigation2018

Diabetic polyneuropathy is a risk factor for decline of lower extremity strength in patients with type 2 diabetes.

Takuo Nomura, Tomoyasu Ishiguro, Masayoshi Ohira, Yukio Ikeda

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of diabetes investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Takuo NomuraDepartment of Rehabilitation Sciences, Kansai University of Welfare Sciences, Osaka, Japan.ORCID http://orcid.org/0000-0001-8781-2877
Tomoyasu IshiguroDepartment of Physical Therapy, Health Science University, Yamanashi, Japan.
Masayoshi OhiraSchool of Health Sciences, Shinshu University, Nagano, Japan.
Yukio IkedaDiabetes Center, Kochi Memorial Hospital, Kochi, Japan.
Kansai University of Welfare Sciences · JPPVS Memorial Hospital · INShinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThe present study elucidated the effect of diabetic polyneuropathy (DPN) on lower extremity strength in a wide age range of type 2 diabetes patients. MATERIALS AND

methodsParticipants (n = 1,442) were divided into three age groups (30-49 years, 50-69 years and 70-87 years), and comparisons were made separately for each sex. Lower extremity strength was measured in terms of knee extension force (KEF) with a hand-held dynamometer. KEF was compared according to the presence or absence of DPN. Furthermore, the effect of DPN on KEF with other diabetic complications (diabetic retinopathy and diabetic nephropathy), diabetes status (diabetes duration and glycated hemoglobin) and habitual behavior (regular exercise, smoking and drinking behaviors) as explanatory variables was analyzed using multiple regression analysis in several models.

resultsThe frequency of DPN differed among age groups, ranging from 14.3 to 49.6%, and increasing with age. There was no significant difference in KEF between patients aged 30-49 years with and without DPN. However, among both men and women aged 50-69 years and 70-87 years, patients with DPN showed significantly diminished KEF (11.0-12.9% and 11.9-16.6%, respectively) compared with those without DPN (P < 0.01-0.001). In women aged 50-69 years and 70-87 years, and in men aged 50-69 years, DPN was a significant explanatory variable for KEF in all multiple regression analysis models.

conclusionDPN might reinforce a KEF decline in middle-aged and elderly type 2 diabetes patients.

Indexed as

Muscle StrengthAdultAgedAged, 80 and overDiabetes Mellitus, Type 2Diabetic NeuropathiesFemaleHumansKneeLower ExtremityMaleMiddle AgedMuscle Strength DynamometerRisk FactorsDiabetic neuropathyMuscle strengthType 2 Diabetes

Identifiers

PMID28296226
PMCPMC5754538
OpenAlexW2599991723

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.