Evidence map›Paper›PMID 28296025›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2017

Renal denervation beyond the bifurcation: The effect of distal ablation placement on safety and blood pressure.

Martine M A Beeftink, Wilko Spiering, Mark R De Jong, Pieter A Doevendans, Peter J Blankestijn, Arif Elvan, Jan-Evert Heeg, Michiel L Bots, Michiel Voskuil

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Safety of catheter-based radiofrequency renal denervation on branch renal arteries in a porcine model.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2019
    Article
  3. Article
  4. Finding the best ablation strategy for renal denervation: A continuing saga.Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Martine M A BeeftinkDepartment of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Wilko SpieringDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Mark R De JongDepartment of Cardiology, Isala Hospital, Zwolle, the Netherlands.
Pieter A DoevendansDepartment of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Peter J BlankestijnDepartment of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands.
Arif ElvanDepartment of Cardiology, Isala Hospital, Zwolle, the Netherlands.
Jan-Evert HeegDepartment of Internal Medicine, Isala Hospital, Zwolle, the Netherlands.
Michiel L BotsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Michiel VoskuilDepartment of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal denervation may be more effective if performed distal in the renal artery because of smaller distances between the lumen and perivascular nerves. The authors reviewed the angiographic results of 97 patients and compared blood pressure reduction in relation to the location of the denervation. No significant differences in blood pressure reduction or complications were found between patient groups divided according to their spatial distribution of the ablations (proximal to the bifurcation in both arteries, distal to the bifurcation in one artery and distal in the other artery, or distal to the bifurcation in both arteries), but systolic ambulatory blood pressure reduction was significantly related to the number of distal ablations. No differences in adverse events were observed. In conclusion, we found no reason to believe that renal denervation distal to the bifurcation poses additional risks over the currently advised approach of proximal denervation, but improved efficacy remains to be conclusively established.

Indexed as

AgedBlood PressureFemaleHumansHypertensionKidneyMaleMiddle AgedNetherlandsRenal ArterySympathectomyhypertension-generaloptimized treatmentrenal denervation

Identifiers

PMID28296025
PMCPMC8030832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.