Evidence map›Paper›PMID 28295468›Full record

ArticleClinical cardiology2017

The protective effects of a novel fitness-fatness index on all-cause mortality among adults with cardiovascular disease.

Emily Frith, Paul D Loprinzi

Abstract read
In one paragraph

Article in Clinical cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  9. Anti-Obesity Effects of Medicinal and Edible Mushrooms.Molecules (Basel, Switzerland) · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emily FrithPhysical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, Mississippi.
Paul D LoprinziPhysical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, Mississippi.ORCID http://orcid.org/0000-0001-7711-4741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the specific association between a fitness-fatness index (FFI) and all-cause mortality among a national sample of US adults with coronary artery disease, congestive heart failure, or myocardial infarction. This FFI has recently emerged in the literature as a novel index of health. HYPOTHESIS: We hypothesize that FFI will be inversely associated with mortality risk.

methodsThe FFI was calculated as cardiorespiratory fitness divided by waist-to-height ratio. Data from the 1999-2006 National Health and Nutrition Examination Survey were used to identify 1206 participants, ages 20 to 85. Person-months of follow-up were calculated from the date of interview until date of death or censoring on December 31, 2011, whichever came first.

resultsIn a Cox proportional hazards model, for every 1-FFI-unit increase, participants had a 6% reduced all-cause mortality rate (hazard ratio [HR]: 0.94, 95% confidence interval [CI]: 0.91-0.97, P = 0.001; N = 1206). Results were similar among those diagnosed with coronary artery disease (HR: 0.94, 95% CI: 0.90-0.98, P = 0.007), congestive heart failure (HR: 0.95, 95% CI: 0.91-0.99, P = 0.02), or myocardial infarction (HR: 0.96, 95% CI: 0.92-0.99, P = 0.04). When examined in isolation, only fitness (and not fatness) was linked with survival benefits.

conclusionsIn this national sample, increased FFI was associated with reduced risk of all-cause mortality; this association was driven by the beneficial effects of fitness. This underscores the importance of tailored cardiac rehabilitation programs designed to promote fitness, in particular, among cardiac populations.

Indexed as

Body Mass IndexNutrition SurveysRisk AssessmentAdultAgedAged, 80 and overCardiovascular DiseasesCause of DeathExercise TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedObesityPhysical FitnessCardiac rehabilitationchronic diseaseEpidemiologyobesityphysical activity

Identifiers

PMID28295468
PMCPMC6490318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.