Evidence map›Paper›PMID 28295375›Full record

ArticleMedical physics2017

X-ray scatter correction for dedicated cone beam breast CT using a forward-projection model.

Linxi Shi, Srinivasan Vedantham, Andrew Karellas, Lei Zhu

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Article
  5. Adaptive proton therapy.Physics in medicine and biology · 2021
    Review
  6. Flat-panel conebeam CT in the clinic: history and current state.Journal of medical imaging (Bellingham, Wash.) · 2021
    Article
  7. Article
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  10. Cone-beam breast computed tomography using ultra-fast image reconstruction with constrained, total-variation minimization for suppression of artifacts.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2020
    Article
  11. Article
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  15. Article
  16. Emerging Breast Imaging Technologies on the Horizon.Seminars in ultrasound, CT, and MR · 2018
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Linxi ShiNuclear and Radiological Engineering and Medical Physics Programs, The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Srinivasan VedanthamDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
Andrew KarellasDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA, 01655, USA.
Lei ZhuNuclear and Radiological Engineering and Medical Physics Programs, The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
University of Massachusetts Chan Medical School · USGeorgia Institute of Technology · USUniversity of Science and Technology of China · CN

Funding

Reducing mastectomy rates in invasive lobular carcinoma by high-resolution 3D breast CTR01CA195512 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI VEDANTHAM, SRINIVASAN · 2015 to 2017
$757k
Role of 3D Tomography in Breast CancerR21CA134128 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GLICK, STEPHEN J, KARELLAS, ANDREW · 2009 to 2010
$723k
Explore random sampling for dose reduction and scatter removal in cone beam CTR21EB021545 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI JIA, XUN, ZHU, LEI · 2016 to 2017
$463k
Volumetric CT Imaging using Primary ModulationR21EB019597 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI ZHU, LEI · 2015 to 2016
$411k
NCI NIH HHS R01 CA195512NCI NIH HHS R21 CA134128NIBIB NIH HHS R21 EB019597NIBIB NIH HHS R21 EB021545
6 · The paper itself

Abstract

purposeThe quality of dedicated cone-beam breast CT (CBBCT) imaging is fundamentally limited by x-ray scatter contamination due to the large irradiation volume. In this paper, we propose a scatter correction method for CBBCT using a novel forward-projection model with high correction efficacy and reliability.

methodWe first coarsely segment the uncorrected, first-pass, reconstructed CBBCT images into binary-object maps and assign the segmented fibroglandular and adipose tissue with the correct attenuation coefficients based on the mean x-ray energy. The modified CBBCT are treated as the prior images toward scatter correction. Primary signals are first estimated via forward projection on the modified CBBCT. To avoid errors caused by inaccurate segmentation, only sparse samples of estimated primary are selected for scatter estimation. A Fourier-Transform based algorithm, herein referred to as local filtration hereafter, is developed to efficiently estimate the global scatter distribution on the detector. The scatter-corrected images are obtained by removing the estimated scatter distribution from measured projection data.

resultsWe evaluate the method performance on six patients with different breast sizes and shapes representing the general population. The results show that the proposed method effectively reduces the image spatial non-uniformity from 8.27 to 1.91% for coronal views and from 6.50 to 3.00% for sagittal views. The contrast-to-deviation ratio is improved by an average factor of 1.41. Comparisons on the image details reveal that the proposed scatter correction successfully preserves fine structures of fibroglandular tissues that are lost in the segmentation process.

conclusionWe propose a highly practical and efficient scatter correction algorithm for CBBCT via a forward-projection model. The method is attractive in clinical CBBCT imaging as it is readily implementable on a clinical system without modifications in current imaging protocols or system hardware.

Indexed as

AlgorithmsCone-Beam Computed TomographyHumansPhantoms, ImagingReproducibility of ResultsScattering, RadiationX-Rayscomputed tomographycone-beam breast CTscatter correctionshading correction

Identifiers

PMID28295375
PMCPMC5994348
OpenAlexW2608338109

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.