Evidence map›Paper›PMID 28295363›Full record

ArticleThe Journal of physiology2017

Angiotensin II activates Ca

Toshihide Kashihara, Tsutomu Nakada, Katsuhiko Kojima, Toshikazu Takeshita, Mitsuhiko Yamada

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Pathogenic CaCommunications biology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. β-Arrestin-Biased ATJACC. Basic to translational science · 2020
    Article
  13. Potential of ATJACC. Basic to translational science · 2020
    Article
  14. Article
  15. Protein Kinase CK2 Controls CaInternational journal of molecular sciences · 2020
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Toshihide KashiharaDepartment of Molecular Pharmacology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Tsutomu NakadaDepartment of Molecular Pharmacology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Katsuhiko KojimaDepartment of Microbiology and Immunology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Toshikazu TakeshitaDepartment of Microbiology and Immunology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Mitsuhiko YamadaDepartment of Molecular Pharmacology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.ORCID 0000-0002-7515-3824
Shinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key pointsAngiotensin II (AngII) is crucial in cardiovascular regulation in perinatal mammalians. Here we show that AngII increases twitch Ca ABSTRACT: Angiotensin II (AngII), the main effector peptide of the renin-angiotensin system, plays important roles in cardiovascular regulation in the perinatal period. Despite the well-known stimulatory effect of AngII on vascular contraction, little is known about regulation of contraction of the immature heart by AngII. Here we found that AngII significantly increased the peak amplitude of twitch Ca

Indexed as

Action PotentialsAngiotensin IIAnimalsbeta-Arrestin 2Calcium Channels, L-TypeCasein Kinase IICells, CulturedCyclin-Dependent Kinase Inhibitor p27HEK293 CellsHumansMaleMiceMice, Inbred C57BLMyocytes, CardiacPhosphorylationProtein BindingAngiotensin IIbeta-Arrestin 2CACNA1C protein, mouseCalcium Channels, L-TypeCasein Kinase IICyclin-Dependent Kinase Inhibitor p27Receptor, Angiotensin, Type 1angiotensin IIcardiomyocytesCaV1.2 Ca2+ channels

Identifiers

PMID28295363
PMCPMC5491886
OpenAlexW2596287968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.