ArticleThe Journal of comparative neurology2017
Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates).
Article in The Journal of comparative neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- A genetic model for development, physiology and behavior of catecholamine-deficient zebrafish larvae.Communications biology · 2026Article
- Resolving forebrain developmental organisation by analysis of differential growth patterns.Nature communications · 2025Article
- Molecular characterization of chicken DA systems reveals that the avian personality gene,Frontiers in neuroanatomy · 2025Article
- Different ways of evolving tool-using brains in teleosts and amniotes.Communications biology · 2024Article
- A Comparison of PKD2L1-Expressing Cerebrospinal Fluid Contacting Neurons in Spinal Cords of Rodents, Carnivores, and Primates.International journal of molecular sciences · 2023Article
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- CRISPR/Cas9-based QF2 knock-in at theFrontiers in neuroanatomy · 2023Article
- Distribution of neurogranin-like immunoreactivity in the brain and sensory organs of the adult zebrafish.The Journal of comparative neurology · 2022Article
- The Neuromeric/Prosomeric Model in Teleost Fish Neurobiology.Brain, behavior and evolution · 2022Review
- Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs.Brain structure & function · 2021Article
- Organization of the Catecholaminergic System in the Short-Lived FishFrontiers in neuroanatomy · 2021Article
- Hypothalamic Dopamine Neurons Control Sensorimotor Behavior by Modulating Brainstem Premotor Nuclei in Zebrafish.Current biology : CB · 2020Article
- Article
- Clearing techniques for visualizing the nervous system in development, injury, and disease.Journal of neuroscience methods · 2020Review
- Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos.Frontiers in neuroanatomy · 2020Article
- Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon.Frontiers in neuroscience · 2020Article
- Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish.Biology open · 2019Article
- Mesencephalic origin of the inferior lobe in zebrafish.BMC biology · 2019Article
- Hydrogel-Tissue Chemistry: Principles and Applications.Annual review of biophysics · 2018Review
- zPACT: Tissue Clearing and Immunohistochemistry on Juvenile Zebrafish Brain.Bio-protocol · 2017Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Cerebrospinal fluid-contacting (CSF-c) cells containing monoamines such as dopamine (DA) and serotonin (5-HT) occur in the periventricular zones of the hypothalamic region of most vertebrates except for placental mammals. Here we compare the organization of the CSF-c cells in chicken, Xenopus, and zebrafish, by analyzing the expression of synthetic enzymes of DA and 5-HT, respectively, tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH), and draw an evolutionary scenario for this cell population. Due to the lack of TH immunoreactivity in this region, the hypothalamic CSF-c cells have been thought to take up DA from the ventricle instead of synthesizing it. We demonstrate that a second TH gene (TH2) is expressed in the CSF-c cells of all the three species, suggesting that these cells do indeed synthetize DA. Furthermore, we found that many CSF-c cells coexpress TH2 and TPH1 and contain both DA and 5-HT, a dual neurotransmitter phenotype hitherto undescribed in the brain of any vertebrate. The similarities of CSF-c cells in chicken, Xenopus, and zebrafish suggest that these characteristics are inherited from the common ancestor of the Osteichthyes. A significant difference between tetrapods and teleosts is that teleosts possess an additional CSF-c cell population around the posterior recess (PR) that has emerged in specific groups of Actinopterygii. Our comparative analysis reveals that the hypothalamus in mammals and teleosts has evolved in a divergent manner: placental mammals have lost the monoaminergic CSF-c cells, while teleosts have increased their relative number.
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