Evidence map›Paper›PMID 28295265›Full record

ArticleEuropean journal of immunology2017

Card9 controls Dectin-1-induced T-cell cytotoxicity and tumor growth in mice.

Tobias Haas, Simon Heidegger, Alexander Wintges, Michael Bscheider, Sarah Bek, Julius C Fischer, Gabriel Eisenkolb, Martina Schmickl, Silvia Spoerl, Christian Peschel and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Loss ofFrontiers in immunology · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. CARD9 Signaling, Inflammation, and Diseases.Frontiers in immunology · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Tobias HaasIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Simon HeideggerIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Alexander WintgesIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Michael BscheiderIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Sarah BekIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Julius C FischerIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Gabriel EisenkolbIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Martina SchmicklIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Silvia SpoerlIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Christian PeschelIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Hendrik PoeckIII. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Jürgen RulandInstitut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität, Munich, Germany.
Technical University of Munich · DEKlinikum rechts der Isar · DEGerman Cancer Research Center · DE

Funding

European Research Council 322865
6 · The paper itself

Abstract

Activation of the C-type lectin receptor Dectin-1 by β-glucans triggers multiple signals within DCs that result in activation of innate immunity. While these mechanisms can potently prime CD8

Indexed as

AnimalsCARD Signaling Adaptor ProteinsCross-PrimingDectin-1Immunity, InnateInflammasomesLectins, C-TypeMiceMice, Inbred C57BLNeoplasmsSignal TransductionT-Lymphocytes, CytotoxicVaccinationCard9 protein, mouseCARD Signaling Adaptor ProteinsDectin-1InflammasomesLectins, C-TypeCard9CD8+ cytotoxic T cellsCross-primingDectin-1Tumor immunity

Identifiers

PMID28295265
PMCPMC5434796
OpenAlexW2591708038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.