Evidence map›Paper›PMID 28295216›Full record

ArticleCancer2017

Genetic alterations in TRAF3 and CYLD that regulate nuclear factor κB and interferon signaling define head and neck cancer subsets harboring human papillomavirus.

Tony Chen, Jialing Zhang, Zhong Chen, Carter Van Waes

Abstract readEditorialComment
In one paragraph

Article in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Emerging Roles of Non-proteolytic Ubiquitination in Tumorigenesis.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Tony ChenTumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Bethesda, Maryland.
Jialing ZhangTumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Bethesda, Maryland.
Zhong ChenTumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Bethesda, Maryland.
Carter Van WaesTumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, Bethesda, Maryland.

Funding

NF-kappaB in pathogenesis and therapy of head and neck cancerZIADC000016 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI VAN WAES, CARTER · 2009 to 2022
$9.3M
Signal and Transcription Factor Network interactions in Head and Neck CancerZIADC000073 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI VAN WAES, CARTER · 2009 to 2022
$9.1M
NF-kappaB in pathogenesis and therapy of head and neck cancerZ01DC000016 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI VAN WAES, CARTER · 1994 to 2008
$2.9M
Signal and Transcription Factor Network interactions in Head and Neck CancerZ01DC000073 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI VAN WAES, CARTER · 2008 to 2008
$607k
Intramural NIH HHS Z01 DC000016Intramural NIH HHS Z01 DC000073Intramural NIH HHS ZIA DC000016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NF-kappa BTNF Receptor-Associated Factor 3Deubiquitinating Enzyme CYLDHead and Neck NeoplasmsHumansInterferonsPapillomaviridaeCYLD protein, humanDeubiquitinating Enzyme CYLDInterferonsNF-kappa BTNF Receptor-Associated Factor 3TRAF3 protein, human

Identifiers

PMID28295216
PMCPMC5419858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.