Evidence map›Paper›PMID 28294549›Full record

ArticleThoracic cancer2017

Clinical and computed tomography findings in Chinese lung cancer patients with HIV infection: A multi-center study.

Zenghui Cheng, Fei Shan, Jinxin Liu, Yuxin Shi, Zhiyong Zhang, Guowei Wu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Thoracic cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zenghui ChengDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Fei ShanDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jinxin LiuDepartment of Radiology, Guangzhou Eighth People's Hospital, Guangzhou, China.
Yuxin ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Zhiyong ZhangDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Guowei WuDepartment of Radiology, Guangxi Longtan Hospital, Liuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study was conducted to investigate clinical and computed tomography (CT) features in Chinese lung cancer patients with human immunodeficiency virus (HIV).

methodsForty consecutive lung cancer patients with HIV were included. Clinical data were collected, and CT features were reviewed and measured. The factors associated with stages of cancer and the CT features with opportunistic pulmonary infections (OPIs) were also analyzed.

resultsThirty-four of the patients were men (85%), and the mean age was 57.5 years. The mean CD4 count was 288 cells/μL, and 23 patients received highly active antiretroviral therapy. OPIs were common (50%). The major histological type (85%) was non-small cell lung cancer (NSCLC), and 15 NSCLC patients (44%) were in stages IIIb and IV. NSCLC patients with an OPI were more common in the advanced stages compared with those without an OPI (P = 0.04). There were no significant differences in advanced and non-advanced stages in terms of CD4 level, highly active antiretroviral therapy, and smoking (P = 0.31, P = 1.00; P = 0.49, respectively). The average size of tumors was 4.5 cm. Irregularly shaped or larger sized tumors were associated with OPIs (P = 0.03, P = 0.04, respectively).

conclusionsThe persistence of locally irregular and large lesions in middle-aged men with HIV and a history of OPIs should be an alert for lung cancer, and clinical management is needed.

Indexed as

AdultAgedAntiretroviral Therapy, Highly ActiveCarcinoma, Non-Small-Cell LungFemaleHIV InfectionsHumansMaleMiddle AgedNeoplasm StagingSmokingTomography, X-Ray ComputedAcquired immunodeficiency syndrome, computed tomography, human immunodeficiency virus, lung cancer

Identifiers

PMID28294549
PMCPMC5415480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.