Evidence map›Paper›PMID 28294469›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Programmable Nanoassemblies from Non-Assembling Homopolymers Using Ad Hoc Electrostatic Interactions.

Jiaming Zhuang, Matteo Garzoni, Diego Amado Torres, Ambata Poe, Giovanni M Pavan, S Thayumanavan

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jiaming ZhuangDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
Matteo GarzoniDepartment of Innovative Technologies, University of Applied Sciences and Arts of Southern Switzerland, Galleria 2, Via Cantonale 2C, Manno, 6928, Switzerland.
Diego Amado TorresDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
Ambata PoeDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
Giovanni M PavanDepartment of Innovative Technologies, University of Applied Sciences and Arts of Southern Switzerland, Galleria 2, Via Cantonale 2C, Manno, 6928, Switzerland.
S ThayumanavanDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA, 01003, USA.ORCID 0000-0002-6475-6726
University of Massachusetts Amherst · USUniversity of Applied Sciences and Arts of Southern Switzerland · CH

Funding

CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
New Amphiphillic Dendrimers for Encapsulation and ReleaseR01GM065255 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THAYUMANAVAN, SANKARAN · 2003 to 2019
$4.3M
NIGMS NIH HHS R01 GM065255NIGMS NIH HHS T32 GM008515
6 · The paper itself

Abstract

Robust nanostructures were obtained from polymers that otherwise do not assemble by using a novel approach based on electrostatic self-assembly. The essence of this strategy involves the use of divalent counterions to temporarily perturb the packing features of the ionic groups in a homopolymer, which results in a vesicle-like structure that is captured in situ through a simple crosslinking reaction. The fidelity of the assembly has been tested for molecular transport across the nanomembrane, both for the molecules encapsulated in the lumen and for those trapped in the membrane itself. The membranes are addressable for robust multifunctionalization of their surfaces and for tunable transmembrane molecular transport.

Indexed as

Static ElectricityNanostructuresParticle SizePolymersSurface PropertiesPolymerselectrostatic interactionshomopolymersprogrammable assembliesself-assembly

Identifiers

PMID28294469
PMCPMC5543410
OpenAlexW2596146725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.