Evidence map›Paper›PMID 28294406›Full record

ArticleClinical & experimental optometry2017

Does transient increase in axial length during accommodation attenuate with age?

Deborah S Laughton, Amy L Sheppard, Edward A H Mallen, Scott A Read, Leon N Davies

Abstract readComparative Study
In one paragraph

Article in Clinical & experimental optometry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Presbyopia: Current Perspectives and Prospects for Patients.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. IMI Accommodation and Binocular Vision in Myopia Development and Progression.Investigative ophthalmology & visual science · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deborah S LaughtonOphthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK.
Amy L SheppardOphthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK.
Edward A H MallenSchool of Optometry and Vision Science, University of Bradford, Bradford, UK.
Scott A ReadInstitute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Park, Queensland, Australia.
Leon N DaviesOphthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim was to profile transient accommodative axial length changes from early adulthood to advanced presbyopia and to determine whether any differences exist between the responses of myopic and emmetropic individuals.

methodsOcular biometry was measured by the LenStar biometer (Haag-Streit, Switzerland) in response to zero, 3.00 and 4.50 D accommodative stimuli in 35 emmetropes and 37 myopes, aged 18 to 60 years. All results were corrected to reduce errors arising from the increase in crystalline lens thickness with accommodation. Accommodative responses were measured sequentially by the WAM 5500 Auto Ref/Keratometer (Grand Seiko, Hiroshima, Japan).

resultsAxial length increased significantly with accommodation (p < 0.001), with a mean corrected increase in axial length of 2 ± 18 µm and 8 ± 16 µm observed at 3.00 and 4.50 D, respectively. The magnitude of accommodative change in axial length was not dependent on refractive error classification (p = 0.959); however, a significant reduction in the magnitude and variance of axial length change was evident after 43 to 44 years of age (p < 0.002).

conclusionThe negative association between transient increase in axial length and age, in combination with reduced variance of data after age 43 to 44 years, is consistent with a significant increase in posterior ocular rigidity, which may be influential in the development of presbyopia.

Indexed as

Accommodation, OcularAdolescentAdultAgingAxial Length, EyeBiometryEmmetropiaFemaleHumansMaleMiddle AgedMyopiaPresbyopiaYoung Adultaccommodationaxial lengthbiometrycrystalline lenspresbyopia

Identifiers

PMID28294406
PMCPMC5697689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.