ArticleScientific reports2017
The highly synergistic, broad spectrum, antibacterial activity of organic acids and transition metals.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 77 citations in OpenAlex.
- Holistic Approaches to Plant Stress Alleviation: A Comprehensive Review of the Role of Organic Compounds and Beneficial Bacteria in Promoting Growth and Health.Plants (Basel, Switzerland) · 2024Review
- Effectiveness of TRIzol in Inactivating Animal Pathogens.Applied biosafety : journal of the American Biological Safety Association · 2023Review
- Efficacy of a New Alcohol-Free Organic Acid-Based Hand Sanitizer against Foodborne Pathogens.Toxics · 2023Article
- Article
- Article
- Antimicrobial activity and chemical profile of wood vinegar from eucalyptus (Eucalyptus urophylla x Eucalyptus grandis - clone I144) and bamboo (Bambusa vulgaris).World journal of microbiology & biotechnology · 2023Article
- Electrospun Polyacrylonitrile Silver(I,III) Oxide Nanoparticle Nanocomposites as Alternative Antimicrobial Materials.ACS omega · 2022Article
- Antibacterial Activity of Electrospun Polyacrylonitrile Copper Nanoparticle Nanofibers on Antibiotic Resistant Pathogens and Methicillin ResistantNanomaterials (Basel, Switzerland) · 2022Article
- An animal derivative-free medium enhances Lactobacillus johnsonii LJO02 supernatant selective efficacy against the methicillin (oxacillin)-resistant Staphylococcus aureus virulence through key-metabolites.Scientific reports · 2022Article
- The lipoprotein NlpD inVirulence · 2021Article
- Further In Vitro Assessment and Mid-Term Evaluation of Control Strategy ofPathogens (Basel, Switzerland) · 2021Article
- Inactivation of Multi-Drug Resistant Non-TyphoidalPathogens (Basel, Switzerland) · 2020Article
- Study of the antibiotic residues in poultry meat in some of the EU countries and selection of the best compositions of lactic acid bacteria and essential oils against Salmonella enterica.Poultry science · 2020Article
- Characterisation of four hotdog-fold thioesterases for their implementation in a novel organic acid production system.Applied microbiology and biotechnology · 2020Article
- Live Bacterial Prophylactics in Modern Poultry.Frontiers in veterinary science · 2020Review
- Evaluating Alternatives to Zinc-Bacitracin Antibiotic Growth Promoter in Broilers: Physiological and Meat Quality Responses.Animals : an open access journal from MDPI · 2019Article
- Acetic Acid Increased the Inactivation of Multi-drug Resistant Non-typhoidalIndian journal of microbiology · 2019Article
- "Smart" Triiodide Compounds: Does Halogen Bonding Influence Antimicrobial Activities?Pathogens (Basel, Switzerland) · 2019Article
- Random peptide mixtures entrapped within a copper-cuprite matrix: new antimicrobial agent against methicillin-resistant Staphylococcus aureus.Scientific reports · 2019Article
- A Combination of Linalool, Vitamin C, and Copper Synergistically Triggers Reactive Oxygen Species and DNA Damage and InhibitsApplied and environmental microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For millennia, transition metals have been exploited to inhibit bacterial growth. We report here the potentiation of the anti-bacterial activity of transition metals by organic acids. Strong synergy between low, non-toxic concentrations of transition metals and organic acids was observed with up to ~1000-fold higher inhibitory effect on bacterial growth. We show that organic acids shuttle transition metals through the permeability barrier of the bacterial membrane, leading to increased influx of transition metals into bacterial cells. We demonstrate that this synergy can be effectively used to inhibit the growth of a broad range of plant and human bacterial pathogens, and suggest that a revision of food preservation and crop protection strategies may be in order. These findings bear significant biomedical, agricultural, financial and environmental opportunities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.