Evidence map›Paper›PMID 28294132›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017

5-HT

Vladimir M Pogorelov, Ramona M Rodriguiz, Jianjun Cheng, Mei Huang, Claire M Schmerberg, Herbert Y Meltzer, Bryan L Roth, Alan P Kozikowski, William C Wetsel

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. Deconstruction of lysergic acid diethylamide.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  4. Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
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  14. Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Vladimir M PogorelovDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Ramona M RodriguizDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Jianjun ChengDrug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-6065-2682
Mei HuangDepartment of Psychiatry and Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Claire M SchmerbergDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Herbert Y MeltzerDepartment of Psychiatry and Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Bryan L RothNational Institute of Mental Health Psychoactive Drug Screening Program, Department of Pharmacology and Division of Chemical Biology and Medicinal Chemistry, University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, USA.
Alan P KozikowskiDrug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, Chicago, IL, USA.
William C WetselDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USDuke University · USNorthwestern University · USUniversity of Illinois Urbana-Champaign · USUniversity of North Carolina at Chapel Hill · US

Funding

Screening CoreU19MH082441 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARON, MARC G., WETSEL, WILLIAM C · 2007 to 2016
$15.2M
Optimizing Lead 5-HT2c Ligands for Use in the Treatment of SchizophreniaR01MH099993 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CALDARONE, BARBARA J., ROTH, BRYAN L. · 2013 to 2016
$2.8M
NIMH NIH HHS R01 MH099993NIMH NIH HHS U19 MH082441
6 · The paper itself

Abstract

All FDA-approved antipsychotic drugs (APDs) target primarily dopamine D

Indexed as

Acoustic StimulationAmphetamineAnimalsBenzazepinesCatalepsyDiscrimination LearningDisease Models, AnimalDrug InteractionsExploratory BehaviorFemaleMaleMiceMice, Inbred C3HMice, Inbred C57BLMotivationNeurotransmitter AgentsAmphetamineBenzazepineslorcaserinNeurotransmitter AgentsSerotonin 5-HT2 Receptor Agonists

Identifiers

PMID28294132
PMCPMC5603814
OpenAlexW2606634315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.