Evidence map›Paper›PMID 28293867›Full record

ArticleGlycoconjugate journal2017

Binding specificity of R-10G and TRA-1-60/81, and substrate specificity of keratanase II studied with chemically synthesized oligosaccharides.

Hiromi Nakao, Yuko Nagai, Aya Kojima, Hidenao Toyoda, Nobuko Kawasaki, Toshisuke Kawasaki

Abstract read
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In one paragraph

Article in Glycoconjugate journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Glycan Markers of Pluripotent Stem Cells.Advances in experimental medicine and biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Expression of Podocalyxin Potentially Decorated With Low-sulfated Keratan Sulfate in Human Testicular Embryonal Carcinoma.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  9. Article
  10. Paradoxical Expression of R-10G-reactive Antigen in Human Testicular Embryonal Carcinoma.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
    Article
  11. Article
  12. Beta3Gn-T7 Is a Keratan Sulfate β1,3Frontiers in neuroanatomy · 2022
    Article
  13. Apical Membrane Expression of Distinct Sulfated Glycans Is a Characteristic Feature of Ductules and Their Reactive and Neoplastic Counterparts.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiromi NakaoResearch Center for Glycobiotechnology, Ritsumeikan University, Noji-Higashi, 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
Yuko NagaiResearch Center for Glycobiotechnology, Ritsumeikan University, Shiga, 525-8577, Japan.
Aya KojimaResearch Center for Glycobiotechnology, Ritsumeikan University, Shiga, 525-8577, Japan.
Hidenao ToyodaResearch Center for Glycobiotechnology, Ritsumeikan University, Shiga, 525-8577, Japan.
Nobuko KawasakiResearch Center for Glycobiotechnology, Ritsumeikan University, Noji-Higashi, 1-1-1, Kusatsu, Shiga, 525-8577, Japan.
Toshisuke KawasakiResearch Center for Glycobiotechnology, Ritsumeikan University, Noji-Higashi, 1-1-1, Kusatsu, Shiga, 525-8577, Japan. tkawasak@fc.ritsumei.ac.jp.ORCID 0000-0003-0993-0274

Funding

A-STEP AS242Z01520PA-STEP AS251Z01560PJapan Society for the Promotion of Science C- 24570171Ministry of Education, Culture, Sports, Science, and Technology of Japan 24110517Mizutani Foundation Research Grant 160204
6 · The paper itself

Abstract

Recently, we established a mouse monoclonal antibody specific to hiPS/ hES cells, R-10G, which recognizes a type of keratan sulfate. Keratan sulfates (KS) comprise a family of glycosaminoglycans consisting of the repeating unit of [Gal-GlcNAc(6S)]. However, there is a diversity in the degree of sulfation at Gal and GlcNAc residues, and also in the mode of linkage, Galβ1 - 3GlcNAc (type 1) or Galβ1 - 4GlcNAc (type 2). To gain more insight into the binding specificity of R-10G, we carried out an ELISA test on avidin-coated plates using polyethylene glycol (PEG)

Indexed as

Antibody SpecificityAcetylglucosaminidaseAnimalsAntibodies, MonoclonalHumansKeratan SulfateSubstrate SpecificityAcetylglucosaminidaseAntibodies, Monoclonalkeratanase IIKeratan SulfateInduced pluripotent stem (iPS) cellsKeratanase IIKeratan sulfatesN-acetyllactosamine tetrasaccharidesR-10GTRA-1-60

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.